{"id":"W2146923745","doi":"10.1189/jlb.0105020","title":"HLA-DO transduced in human monocyte-derived dendritic cells modulates MHC class II antigen processing","year":2005,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Royal Victoria Hospital; McGill University Health Centre; Hôpital Saint-Luc; Centre Hospitalier de l’Université de Montréal; Royal Victoria Regional Health Centre; Université de Montréal","funders":"Cancer Research Society","keywords":"Biology; Antigen presentation; MHC class II; Major histocompatibility complex; Antigen processing; Antigen; Cell biology; Human leukocyte antigen; CD74; Monocyte; Molecular biology; Dendritic cell; CD8; Antigen-presenting cell; T cell; MHC class I; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007769383,0.0001821641,0.0001654744,0.00007279794,0.00008827968,0.000269593,0.0000782921,0.00015114,0.000863937],"category_scores_gemma":[0.00006860522,0.0000794301,0.0001205027,0.0001081391,0.0001116476,0.0000958055,0.00009787673,0.0003932232,0.0002628363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573087,"about_ca_system_score_gemma":0.0001218458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002043397,"about_ca_topic_score_gemma":0.0002837862,"domain_scores_codex":[0.999905,0.00001598018,0.000008399923,0.00001873016,0.0000160675,0.00003585934],"domain_scores_gemma":[0.9999421,0.00001147281,0.00001305899,0.000008794157,0.000005542831,0.00001908706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008060739,0.00002443428,0.0001143305,0.00001598672,0.000001648229,0.00002993619,0.000008038641,0.00002071141,0.999213,0.00005729908,0.00001514402,0.0004189049],"study_design_scores_gemma":[0.00002430222,0.0003251241,0.00288788,0.000003640335,0.00001514738,0.0001129091,0.00002800771,0.0005503978,0.9942221,0.00003720898,0.001790843,0.000002422702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976307,0.0004094547,0.0008153535,0.00003783377,0.00002608289,0.00001533746,0.0001787024,0.00001850416,0.0008679629],"genre_scores_gemma":[0.9973379,0.0004591132,0.00080154,0.00004619264,0.00001168147,0.00001593181,0.000264528,0.000008809917,0.001054277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000863937,"threshold_uncertainty_score":0.00289017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01727484495057762,"score_gpt":0.2748301933942982,"score_spread":0.2575553484437205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}