{"id":"W2146962291","doi":"10.1016/j.jtbi.2006.05.012","title":"Dynamics, stability and inheritance of somatic DNA methylation imprints","year":2006,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Leukemia and Lymphoma Society","keywords":"Epigenetics; DNA methylation; Biology; Methylation; CpG site; Epigenetics of physical exercise; Chromatin; Genomic imprinting; Genetics; Gene silencing; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005183642,0.0001302296,0.0003117271,0.0006725403,0.0003806759,0.001131659,0.0006008891,0.0004956734,0.002143105],"category_scores_gemma":[0.00481466,0.000339295,0.000201598,0.0003753924,0.001083612,0.001473416,0.0004775572,0.0005915212,0.0002580163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007421397,"about_ca_system_score_gemma":0.0003419101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009110651,"about_ca_topic_score_gemma":0.0006188747,"domain_scores_codex":[0.9998643,0.00002043532,0.000005272822,0.0000444724,0.00003388539,0.00003166615],"domain_scores_gemma":[0.9983012,0.0009761157,0.00028624,0.0001425896,0.0001311899,0.0001627486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007488093,0.0001591413,0.04469592,0.0002197436,0.0001272032,0.0005031462,0.0008189358,0.1202882,0.2497377,0.5288066,0.002555287,0.05133924],"study_design_scores_gemma":[0.0000739136,0.0001661943,0.04602089,0.00001716624,0.0000598437,0.0006086554,0.0002926023,0.65002,0.04480029,0.2556498,0.002192361,0.00009828973],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811773,0.0004084682,0.01479804,0.0004823022,0.00001835073,0.000004412693,0.0001283781,0.00008412157,0.002898501],"genre_scores_gemma":[0.9986285,0.0001175293,0.0006148232,0.000007247187,0.00001017712,0.000003717548,0.00003968142,0.00001036783,0.0005681394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002143105,"threshold_uncertainty_score":0.007169425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006555913294153918,"score_gpt":0.2542354285860963,"score_spread":0.2476795152919424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}