{"id":"W2146962291","doi":"10.1016/j.jtbi.2006.05.012","title":"Dynamics, stability and inheritance of somatic DNA methylation imprints","year":2006,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Leukemia and Lymphoma Society","keywords":"Epigenetics; DNA methylation; Biology; Methylation; CpG site; Epigenetics of physical exercise; Chromatin; Genomic imprinting; Genetics; Gene silencing; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006653935,0.00008229582,0.000204803,0.00003945693,0.00002028089,0.000005533899,0.00009549744,0.0001520189,0.0000238461],"category_scores_gemma":[0.0003375468,0.0000646618,0.00007421873,0.00004422236,0.0004112408,0.000003129651,0.00005012835,0.00007935269,4.251864e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001452164,"about_ca_system_score_gemma":0.00002993715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004079358,"about_ca_topic_score_gemma":0.000008552858,"domain_scores_codex":[0.9990641,0.0001773164,0.0004591453,0.0001195253,0.00006761219,0.0001122857],"domain_scores_gemma":[0.9992707,0.00007822648,0.0002933978,0.0001371243,0.000177215,0.00004336574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008367879,0.00005578802,0.02502489,0.00001795441,0.00002185975,4.439266e-7,0.00001017418,0.000009074592,0.9029523,0.0694313,0.000003521552,0.002389036],"study_design_scores_gemma":[0.0003582373,0.0005473623,0.02110486,0.000009546066,0.00002354115,0.000007977244,0.0000238483,0.0002614955,0.7227995,0.2546905,0.00009789873,0.00007524726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978012,0.001336822,0.01964464,0.0002397236,0.0001217572,0.00005800401,0.0000107836,0.000001411846,0.0005748412],"genre_scores_gemma":[0.9971704,0.0001843141,0.002470258,0.00001278209,0.0001347491,7.291498e-7,0.00001465339,0.000006543925,0.000005524368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1852592,"threshold_uncertainty_score":0.2636832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006555913294153918,"score_gpt":0.2542354285860963,"score_spread":0.2476795152919424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}