{"id":"W2147008159","doi":"10.1016/s0378-1097(03)00474-9","title":"BldD from<i>Streptomyces coelicolor</i>is a non-essential global regulator that binds its own promoter as a dimer","year":2003,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Streptomyces coelicolor; Tetramer; Dimer; Regulator; Gene; Genetics; Biology; Streptomyces; Chemistry; Biochemistry; Bacteria; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001950496,0.0004844182,0.0006862368,0.0001084171,0.00016732,0.00005392975,0.0002703689,0.000494175,0.002551785],"category_scores_gemma":[0.0000995052,0.0003559938,0.0002960734,0.0003053466,0.0003638484,0.0001139206,0.0001037336,0.0004000239,0.00104972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001358249,"about_ca_system_score_gemma":0.0001233127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001708569,"about_ca_topic_score_gemma":0.00001689087,"domain_scores_codex":[0.9975469,0.000146874,0.00041119,0.001016477,0.0001248566,0.0007537223],"domain_scores_gemma":[0.9988483,0.00005050046,0.0002213361,0.0005849487,0.00009991561,0.0001949606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002847884,0.0001376405,0.004266911,0.00002925619,0.0003604009,0.00009017222,0.000153598,1.601572e-7,0.872891,0.00001133081,0.121398,0.000376732],"study_design_scores_gemma":[0.00155604,0.0002062465,0.002664268,0.0001096529,0.0002546787,0.0005058932,0.00003266258,0.000001914241,0.8758187,0.00001838314,0.1184111,0.0004204942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700164,0.0006280709,0.000009057659,0.02653633,0.001189626,0.0007781285,0.0002887667,0.000100393,0.0004531999],"genre_scores_gemma":[0.9698879,0.00003734159,0.0006337857,0.02736838,0.0004949986,0.000006716994,0.0002237062,0.00003882186,0.001308401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002986937,"threshold_uncertainty_score":0.9998892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009649247437377738,"score_gpt":0.2383222401683189,"score_spread":0.2286729927309412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}