{"id":"W2147045937","doi":"10.1007/s00424-008-0634-y","title":"Regulation of wild-type and mutant KCNQ1/KCNE1 channels by tyrosine kinase","year":2009,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Tyrosine; Phosphorylation; Tyrosine phosphorylation; Protein tyrosine phosphatase; Tyrosine kinase; Biology; Tyrosine-kinase inhibitor; Cell biology; Biochemistry; Chemistry; Molecular biology; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004997339,0.0003405438,0.0002918316,0.0001864967,0.0002830485,0.0005061465,0.0004949277,0.0003521421,0.001696821],"category_scores_gemma":[0.0005260971,0.0001743637,0.0003460549,0.0001500543,0.0004875645,0.0005400927,0.0002647687,0.0006813951,0.0002850971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008707705,"about_ca_system_score_gemma":0.0002428625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084689,"about_ca_topic_score_gemma":0.001499846,"domain_scores_codex":[0.9996425,0.000076739,0.00003940027,0.00006153251,0.00007147031,0.0001083188],"domain_scores_gemma":[0.9996784,0.0001368817,0.00006181747,0.00004687659,0.00002694593,0.00004914039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005769941,0.00004474075,0.0001502484,0.00003265954,0.000006374977,0.00004096299,0.00004122014,0.0001399327,0.9978041,0.0005711947,0.00005893497,0.0005325296],"study_design_scores_gemma":[0.0001349221,0.0001561498,0.005229284,0.000008563865,0.00002091053,0.0003182765,0.00008050913,0.004803452,0.9871001,0.0001722858,0.001960237,0.0000152214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973986,0.0009275008,0.0007917384,0.0001028367,0.00004085079,0.00001163327,0.0001811974,0.0000207376,0.000524856],"genre_scores_gemma":[0.9974031,0.0004128793,0.0008347131,0.0000456471,0.00001090431,0.0000264285,0.000357175,0.00002934161,0.0008798076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001696821,"threshold_uncertainty_score":0.006317854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008328940874841215,"score_gpt":0.2324815733344707,"score_spread":0.2241526324596295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}