{"id":"W2147054306","doi":"10.1016/j.cell.2007.05.052","title":"Systematic Discovery of In Vivo Phosphorylation Networks","year":2007,"lang":"en","type":"article","venue":"Cell","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":749,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Phosphorylation; Biology; Kinase; Computational biology; Cyclin-dependent kinase 1; Protein phosphorylation; Cell biology; Context (archaeology); Protein-Serine-Threonine Kinases; Proteome; In vivo; Dephosphorylation; Biochemistry; Protein kinase A; Genetics; Phosphatase; Gene; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008178751,0.0007303098,0.0009339041,0.001727149,0.0005296731,0.001242308,0.001002521,0.0005888927,0.001201352],"category_scores_gemma":[0.004193782,0.0005357287,0.0008653979,0.001518853,0.0005118786,0.001357474,0.0008631985,0.001232052,0.0004886968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007261166,"about_ca_system_score_gemma":0.001102461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001041918,"about_ca_topic_score_gemma":0.003700315,"domain_scores_codex":[0.9994386,0.0002085935,0.00002561195,0.0001838322,0.0001051835,0.00003810565],"domain_scores_gemma":[0.9972609,0.001631703,0.0003344347,0.0005144787,0.0001542294,0.0001042664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001455158,0.000592978,0.05535818,0.002574633,0.001286967,0.00140771,0.0003406287,0.2932001,0.3471197,0.1124952,0.01019501,0.1739738],"study_design_scores_gemma":[0.00009252444,0.0001093712,0.01425928,0.00004349979,0.0003128113,0.000385741,0.0001096249,0.789492,0.06701764,0.1202263,0.00791681,0.00003441418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5118242,0.003078488,0.4603909,0.001404349,0.0001050507,0.0001270021,0.014539,0.003873582,0.004657428],"genre_scores_gemma":[0.8682558,0.001863079,0.1168284,0.0001801801,0.00005127097,0.0000896912,0.01185078,0.0002648243,0.0006160472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001727149,"threshold_uncertainty_score":0.005268395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003931546081518315,"score_gpt":0.1983639097697098,"score_spread":0.1944323636881914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}