{"id":"W2147055142","doi":"10.1111/acel.12402","title":"Homeostatic dysregulation proceeds in parallel in multiple physiological systems","year":2015,"lang":"en","type":"article","venue":"Aging Cell","topic":"Aging and Gerontology Research","field":"Psychology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute on Aging; Fonds de Recherche du Québec - Santé; Anatomical Society; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research","keywords":"Immune dysregulation; Disease; Biomarker; Biology; Immune system; Medicine; Immunology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002725295,0.0004256523,0.0008950573,0.001109777,0.0004295505,0.001453295,0.0004532004,0.0003634191,0.0006786408],"category_scores_gemma":[0.004822334,0.0004457624,0.0006566109,0.0008259848,0.001444484,0.001505368,0.002081565,0.0009132126,0.0002083776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006610114,"about_ca_system_score_gemma":0.0005727087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001292481,"about_ca_topic_score_gemma":0.001412449,"domain_scores_codex":[0.9979309,0.0005824763,0.0001829785,0.000785967,0.0004053296,0.0001123828],"domain_scores_gemma":[0.996009,0.001246313,0.001281269,0.0008001488,0.0004456188,0.0002177081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008666712,0.000264297,0.7790709,0.000532913,0.001429341,0.0004045956,0.002243646,0.009684025,0.1318649,0.004348867,0.0007202392,0.06856967],"study_design_scores_gemma":[0.00001321744,0.0002708918,0.9730359,0.00003586508,0.0001730785,0.0002885218,0.0002723912,0.009265034,0.006636948,0.008676391,0.001280622,0.00005109906],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9608904,0.001447211,0.03458916,0.0003130609,0.00002984667,0.00009129327,0.0005713483,0.0002808506,0.001786678],"genre_scores_gemma":[0.9876884,0.0003236307,0.01096033,0.0001466291,0.00001825856,0.00005418333,0.0005617082,0.0000251692,0.0002216524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002725295,"threshold_uncertainty_score":0.01441288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1338669439957625,"score_gpt":0.3644733197829984,"score_spread":0.2306063757872359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}