{"id":"W2147093282","doi":"10.1128/jvi.79.10.6078-6088.2005","title":"Nuclear Localization of the Nipah Virus W Protein Allows for Inhibition of both Virus- and Toll-Like Receptor 3-Triggered Signaling Pathways","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virology and Viral Diseases","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Cleveland Clinic; McGill University; Cleveland Clinic Foundation; Ellison Medical Foundation","keywords":"Biology; Nuclear localization sequence; Karyopherin; IRF3; TLR3; Signal transduction; Nuclear export signal; Nuclear transport; Cell biology; Molecular biology; Nuclear protein; Importin; Cytoplasm; Toll-like receptor; Cell nucleus; Receptor; Gene; Biochemistry; Transcription factor; Innate immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003796251,0.0001040888,0.0003901683,0.0001142024,0.00006740841,0.000003164019,0.00007026857,0.000186959,0.0001289104],"category_scores_gemma":[0.0002114041,0.00007142111,0.0001647458,0.00008154748,0.0002072489,0.0001088617,0.00002767522,0.0001776436,0.000001846135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002603266,"about_ca_system_score_gemma":0.00008118748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007178991,"about_ca_topic_score_gemma":0.00001403244,"domain_scores_codex":[0.9988611,0.0001460297,0.0005884644,0.0001081321,0.0001554499,0.0001407731],"domain_scores_gemma":[0.9989625,0.00006684211,0.0006392098,0.0001158309,0.0001437902,0.00007182356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003550747,0.0003442702,0.001172455,0.0001019656,0.00009710769,0.000004373058,0.00026598,0.0003013785,0.9911553,0.0003861132,0.0009756681,0.001644685],"study_design_scores_gemma":[0.01319002,0.0108592,0.01875798,0.0007246317,0.001032604,0.0002890756,0.0003040541,0.004928367,0.922207,0.00323338,0.02417667,0.000297004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963693,0.0006495691,0.00137353,0.001058421,0.00009489055,0.0003827971,0.00003518478,0.000006031069,0.00003030095],"genre_scores_gemma":[0.9975415,0.0001258834,0.0009107487,0.001168887,0.0002005454,0.000005443776,0.000005291648,0.00001611057,0.00002558057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06894824,"threshold_uncertainty_score":0.2912468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01720981756880473,"score_gpt":0.2514832146019439,"score_spread":0.2342733970331392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}