{"id":"W2147095990","doi":"10.1093/jmcb/mjp025","title":"The TET Family of Proteins: Functions and Roles in Disease","year":2009,"lang":"en","type":"review","venue":"Journal of Molecular Cell Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Fusion protein; RNA splicing; Gene; Transcription factor; Genetics; SR protein; Transcription (linguistics); RNA polymerase II; Alternative splicing; RNA-binding protein; Computational biology; DNA-binding protein; Gene expression; Cell biology; RNA; Messenger RNA; Promoter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002756273,0.0007377259,0.001106301,0.001566285,0.0002476679,0.0007087596,0.0006813208,0.0008697789,0.002382291],"category_scores_gemma":[0.0002897774,0.0002232652,0.0002461261,0.001815741,0.0004985394,0.001316968,0.0004853915,0.00124418,0.002717087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005642758,"about_ca_system_score_gemma":0.0005916985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005846097,"about_ca_topic_score_gemma":0.001094512,"domain_scores_codex":[0.9999112,0.0000112507,0.00001227909,0.00001765346,0.00003599058,0.00001167785],"domain_scores_gemma":[0.9998891,0.00004124573,0.00001715905,0.000003772753,0.00003018123,0.00001846074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000707635,0.00005235763,0.0001868359,0.006932397,0.00003893951,0.0003522358,0.00006050962,0.0003166546,0.004570326,0.002608269,0.02626772,0.9585431],"study_design_scores_gemma":[0.00001370903,0.00006009443,0.0009702033,0.001027165,0.00004294685,0.00227556,0.00005881845,0.00005462842,0.000684395,0.001404161,0.9933944,0.00001380387],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000226666,0.9980332,0.0001684808,0.000233794,0.000187022,0.000003653969,0.00001575219,0.00001130378,0.001120117],"genre_scores_gemma":[0.0008147863,0.9977067,0.0002348308,0.0001478966,0.0001025154,0.000005530962,0.00003043883,0.000001778779,0.0009555902],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002382291,"threshold_uncertainty_score":0.007969499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009961416181039347,"score_gpt":0.2665866831609613,"score_spread":0.256625266979922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}