{"id":"W2147143140","doi":"10.1093/glycob/cwl049","title":"Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase","year":2006,"lang":"en","type":"article","venue":"Glycobiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Tropomyosin receptor kinase A; Tropomyosin receptor kinase B; Trk receptor; Sialidase; Chemistry; Neurotrophin; Nerve growth factor; Low-affinity nerve growth factor receptor; Tropomyosin receptor kinase C; Receptor; Receptor tyrosine kinase; Ganglioside; Cell biology; Brain-derived neurotrophic factor; Neuraminidase; Biochemistry; Neurotrophic factors; Biology; Platelet-derived growth factor receptor; Growth factor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001110083,0.0001439026,0.0002002738,0.000114895,0.0000399375,0.000004901298,0.0001859172,0.0002202252,0.0001478488],"category_scores_gemma":[0.0001894591,0.0001294794,0.00009244465,0.0001581281,0.0001565483,0.00000405528,0.00006363369,0.0001135617,0.00001565696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001325649,"about_ca_system_score_gemma":0.00006445168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002050931,"about_ca_topic_score_gemma":0.00001851131,"domain_scores_codex":[0.9988315,0.0001566476,0.0003232386,0.0003148075,0.0001492341,0.0002245616],"domain_scores_gemma":[0.9992204,0.00003221994,0.0001832141,0.0003491078,0.0001687083,0.00004638896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004739651,0.0001434259,0.002092547,0.00002671731,0.00001234237,0.000002468354,0.000006858367,0.0002269001,0.9949583,0.0004695897,0.0003953652,0.001191501],"study_design_scores_gemma":[0.0006332487,0.001001482,0.004259863,0.00001592932,0.000004108892,0.000002730407,0.000006935075,0.00003443315,0.9858609,0.00009788229,0.007971048,0.0001114837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977521,0.0001185897,0.0008067277,0.0001078817,0.0001581173,0.000266897,0.00005008187,0.000009050769,0.0007305746],"genre_scores_gemma":[0.9987969,0.0000329532,0.0001780344,0.00004899375,0.0001498436,0.00001626558,0.0002801531,0.00001584496,0.0004810023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009097463,"threshold_uncertainty_score":0.5280015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01393392627756527,"score_gpt":0.2548983279929375,"score_spread":0.2409644017153723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}