{"id":"W2147147806","doi":"10.1124/dmd.105.004374","title":"CANCER CHEMOTHERAPY AND DRUG METABOLISM","year":2005,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Prodrug; Pharmacology; Drug metabolism; Drug; Pharmacokinetics; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003600926,0.0001774354,0.0002795324,0.0005875419,0.0002138718,0.001207626,0.0001436125,0.0004394211,0.009029679],"category_scores_gemma":[0.001497162,0.0001277084,0.0002601376,0.001066915,0.0003232364,0.0004439276,0.0003214601,0.0005274065,0.001251858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0010609,"about_ca_system_score_gemma":0.0006898643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003145239,"about_ca_topic_score_gemma":0.003622315,"domain_scores_codex":[0.9995905,0.0002216411,0.00002896461,0.00004951861,0.00007799568,0.00003136307],"domain_scores_gemma":[0.9992775,0.000272026,0.0002532814,0.00004507804,0.00008834626,0.00006370757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002802511,0.0005320841,0.3174657,0.001252691,0.0009380179,0.002796733,0.0003367771,0.003676418,0.01700443,0.03853787,0.02886907,0.5857877],"study_design_scores_gemma":[0.0001576316,0.001283099,0.532984,0.0004987013,0.0006488913,0.01084887,0.0003390193,0.003338324,0.009093921,0.0262909,0.4144545,0.00006201642],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3025932,0.5421699,0.003744043,0.02260173,0.0006827092,0.00009861097,0.001860559,0.0001582606,0.1260909],"genre_scores_gemma":[0.8675416,0.1061348,0.0009820781,0.001947481,0.0005264806,0.00003078802,0.0005375036,0.00002586092,0.02227347],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009029679,"threshold_uncertainty_score":0.03020734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03125667228027106,"score_gpt":0.3759516955180336,"score_spread":0.3446950232377626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}