{"id":"W2147204536","doi":"10.1021/bi052322r","title":"2‘-Fluoroarabino- and Arabinonucleic Acid Show Different Conformations, Resulting in Deviating RNA Affinities and Processing of Their Heteroduplexes with RNA by RNase H<sup>,</sup>","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Institute of General Medical Sciences","keywords":"RNA; RNase P; RNase H; DNA; Chemistry; Stereochemistry; Binding affinities; Affinities; Molecular biology; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001278345,0.0001964337,0.000101434,0.0001118434,0.0001032463,0.0002086303,0.0001656392,0.0002063623,0.001101833],"category_scores_gemma":[0.000251343,0.0001683343,0.0001087686,0.0001199065,0.000209405,0.000192962,0.00008408708,0.0002237805,0.0002458388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002181393,"about_ca_system_score_gemma":0.0000859736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003878801,"about_ca_topic_score_gemma":0.0007301808,"domain_scores_codex":[0.9999186,0.0000187102,0.000004578831,0.00002417118,0.00001691998,0.00001711597],"domain_scores_gemma":[0.9998541,0.00004665072,0.00004207096,0.00001580099,0.00001076635,0.00003065734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001625722,0.00001358499,0.0006840975,0.00001558588,0.000007369039,0.00004037217,0.00002012595,0.0001346812,0.9970497,0.0003150619,0.0000224206,0.001534348],"study_design_scores_gemma":[0.00001639646,0.0002173688,0.005753046,0.000002752997,0.000007569722,0.0004224583,0.00002774064,0.001066274,0.9904774,0.0001367289,0.001865794,0.000006458057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965848,0.0003033309,0.001736761,0.0000200471,0.00000602108,0.00000465887,0.00004363083,0.00002488756,0.001275798],"genre_scores_gemma":[0.9964938,0.0001133306,0.002563697,0.00002608521,0.000002278502,0.000009060755,0.0001710781,0.00001258621,0.0006080764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101833,"threshold_uncertainty_score":0.003685951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00487551988243698,"score_gpt":0.1917947741893918,"score_spread":0.1869192543069549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}