{"id":"W2147208965","doi":"10.1093/hmg/ddr478","title":"Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations","year":2011,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Medical Research Council; National Institute on Alcohol Abuse and Alcoholism; National Health and Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Australian Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Raine Medical Research Foundation; U.S. Public Health Service; QIMR Berghofer Medical Research Institute","keywords":"Biology; Locus (genetics); Genetics; Single-nucleotide polymorphism; SNP; Disease; Chromosome 12; Chromosome; Gene; Internal medicine; Genotype; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006646958,0.0001579604,0.000224404,0.0001417706,0.00007115478,0.00002812497,0.00003035815,0.00005017939,0.00001360233],"category_scores_gemma":[0.00002635876,0.0001595616,0.00007914237,0.00009691645,0.00004038799,0.00004033203,0.00002843998,0.000101642,0.000002727725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005351404,"about_ca_system_score_gemma":0.00001925103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001027709,"about_ca_topic_score_gemma":0.0000767743,"domain_scores_codex":[0.9991109,0.00008515535,0.000171821,0.0002846011,0.0001606625,0.0001869101],"domain_scores_gemma":[0.9994681,0.00001146044,0.00003951144,0.0001809714,0.00003723829,0.0002626599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001196292,0.0008357622,0.9847726,0.0002547572,0.0001688663,0.0006023585,0.002364168,0.00000756176,0.002115984,0.0001263669,0.00001163051,0.008620345],"study_design_scores_gemma":[0.002361141,0.0001265221,0.9950314,0.0002880479,0.0004987109,0.000004832524,0.0001593993,0.0001007281,0.001150855,0.000118867,0.00002246805,0.000137075],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968123,0.002227997,0.00006957614,0.00002808824,0.00003657565,0.0004918183,0.00002895743,0.0000231344,0.0002814927],"genre_scores_gemma":[0.9990427,0.0004985526,0.0001476481,0.0001191608,0.00003670042,0.00003756214,0.0000847636,0.00002630524,0.00000653926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01025878,"threshold_uncertainty_score":0.6506734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02966349161657052,"score_gpt":0.2802033442750844,"score_spread":0.2505398526585139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}