{"id":"W2147227398","doi":"10.1093/cercor/bhq018","title":"Transient Swelling, Acidification, and Mitochondrial Depolarization Occurs in Neurons but not Astrocytes during Spreading Depression","year":2010,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Fondation Leducq; Michael Smith Health Research BC; Heart and Stroke Foundation of Canada","keywords":"Depolarization; Cortical spreading depression; Neuroscience; Membrane potential; Electrophysiology; Extracellular; Biophysics; Mitochondrion; Astrocyte; Intracellular; Neuron; Biology; Chemistry; Cell biology; Central nervous system; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001018925,0.0001788553,0.0001597622,0.0002542894,0.0004153689,0.000129978,0.0003541061,0.00009852045,0.00004973311],"category_scores_gemma":[0.0003987359,0.0001724629,0.00004042105,0.0004302608,0.0002849335,0.0004913856,0.0001052532,0.0007459192,0.00002037877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001528789,"about_ca_system_score_gemma":0.00005625889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001864944,"about_ca_topic_score_gemma":0.00003606111,"domain_scores_codex":[0.9979072,0.0001676028,0.0002876756,0.0008078605,0.000337206,0.0004924362],"domain_scores_gemma":[0.9992381,0.0001914178,0.00008943219,0.0002559049,0.00002948056,0.0001956526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001386609,0.00006293051,0.02400595,0.00001338105,5.037896e-7,0.00005084767,0.0001221491,0.00002739585,0.9749648,0.00007226116,0.00000975923,0.0005313925],"study_design_scores_gemma":[0.0007040509,0.00005300733,0.1578002,0.000009013972,0.000005401587,0.00008172742,0.00001200074,0.002717074,0.8384098,0.00001198411,0.0000660173,0.000129808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979826,0.00000886258,0.0001971093,0.0001977961,0.001008257,0.0004088349,0.00001119949,0.00007896073,0.0001064332],"genre_scores_gemma":[0.9992021,0.00005749064,0.00007987266,0.0003081207,0.0001354436,0.00002881046,0.000001458398,0.00002401688,0.0001626775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.136555,"threshold_uncertainty_score":0.7032831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02669176100060753,"score_gpt":0.295125506897781,"score_spread":0.2684337458971734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}