{"id":"W2147257532","doi":"10.1155/2009/315687","title":"Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report","year":2009,"lang":"en","type":"article","venue":"Case Reports in Medicine","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; University of Toronto; University Health Network","funders":"","keywords":"Ketoconazole; Warfarin; Medicine; Pharmacology; Adverse effect; Internal medicine; Antifungal; Dermatology; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002219857,0.0003172513,0.0006338699,0.0002975963,0.0001848881,0.00001308027,0.00005741938,0.0002963914,0.0005602421],"category_scores_gemma":[0.0004867752,0.0002799321,0.00005360144,0.0003169277,0.0002303769,0.000131974,0.00006444063,0.001002594,0.000006121921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007981461,"about_ca_system_score_gemma":0.00008031452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003043313,"about_ca_topic_score_gemma":0.00004483092,"domain_scores_codex":[0.9972349,0.000273526,0.00120648,0.0006206603,0.0002090322,0.0004553423],"domain_scores_gemma":[0.9982021,0.0003133508,0.0005058828,0.0003968493,0.0001260024,0.0004557983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00009634971,0.0001195522,0.00192542,0.00002690153,0.00006059317,0.8219182,0.0008096785,0.00006241846,0.02059368,0.00006581329,0.000841214,0.1534801],"study_design_scores_gemma":[0.002763666,0.0001798423,0.004361022,0.00006056734,0.0003924975,0.9144171,0.0003957799,0.000443543,0.02881007,0.001371731,0.04646892,0.0003352286],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887944,0.001816873,0.000293798,0.001616638,0.002119415,0.0006844429,0.000009329813,0.00007801605,0.004587016],"genre_scores_gemma":[0.9960517,0.0004536677,0.0001675823,0.001605883,0.001150868,0.00005275308,0.00004829955,0.00002227976,0.0004469354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1531449,"threshold_uncertainty_score":0.9999653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1075763172649378,"score_gpt":0.4695814192466626,"score_spread":0.3620051019817248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}