{"id":"W2147267978","doi":"10.1128/aem.67.10.4488-4494.2001","title":"Differential Effects of pH on the Pore-Forming Properties of <i>Bacillus thuringiensis</i> Insecticidal Crystal Toxins","year":2001,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute; Université de Montréal","funders":"","keywords":"Bacillus thuringiensis; Cry1Ac; Manduca sexta; Manduca; Midgut; Toxin; Brush border; Biophysics; Vesicle; Chemistry; Chromatography; Biology; Biochemistry; Membrane; Botany; Insect; Bacteria; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003094807,0.0001447289,0.000164724,0.0000208884,0.00006892972,0.000003330751,0.0001030652,0.000119316,0.00001291619],"category_scores_gemma":[0.000005027837,0.00009794704,0.00005495851,0.0000222241,0.0003648795,0.000001302672,0.0001188461,0.0000694476,0.000001575904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008166498,"about_ca_system_score_gemma":0.000008279528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006657783,"about_ca_topic_score_gemma":0.000008233886,"domain_scores_codex":[0.9993713,0.00002494908,0.0001688857,0.0002064031,0.00003867582,0.000189751],"domain_scores_gemma":[0.9996895,0.0000148824,0.00008244561,0.0001855989,0.000003582326,0.00002395432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002010501,0.0001030677,0.0006342934,0.00003616057,0.00005281805,0.000001475217,0.0001298644,0.000007623988,0.9980124,0.00008635659,0.00003118274,0.0007037285],"study_design_scores_gemma":[0.0004652186,0.0003835337,0.001959241,0.00001438601,0.00002165428,0.00003521332,0.0001708902,0.000001373984,0.9953066,0.00002275403,0.001505718,0.000113489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998778,0.0004513233,0.00005150695,0.00002077838,0.00005926176,0.0002025714,0.00002052,0.000002850646,0.0004132261],"genre_scores_gemma":[0.9991624,0.0004295803,0.00002134016,0.0001688839,0.00005652778,0.00001404783,0.00005597524,0.00001242228,0.00007880784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00270585,"threshold_uncertainty_score":0.3994164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004003301568358161,"score_gpt":0.1557385319489841,"score_spread":0.151735230380626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}