{"id":"W2147267978","doi":"10.1128/aem.67.10.4488-4494.2001","title":"Differential Effects of pH on the Pore-Forming Properties of <i>Bacillus thuringiensis</i> Insecticidal Crystal Toxins","year":2001,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute; Université de Montréal","funders":"","keywords":"Bacillus thuringiensis; Cry1Ac; Manduca sexta; Manduca; Midgut; Toxin; Brush border; Biophysics; Vesicle; Chemistry; Chromatography; Biology; Biochemistry; Membrane; Botany; Insect; Bacteria; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003571148,0.0003248277,0.0002702546,0.0001263514,0.00008337526,0.0004443577,0.0002160959,0.0002999753,0.0008024563],"category_scores_gemma":[0.0007397601,0.0002063471,0.0002138372,0.0001293233,0.0002261556,0.0004064785,0.0002380805,0.0004333555,0.0001927939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001867377,"about_ca_system_score_gemma":0.0001023276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005164576,"about_ca_topic_score_gemma":0.0004303316,"domain_scores_codex":[0.9996791,0.00008606453,0.00003617229,0.00004984036,0.00007722607,0.00007160249],"domain_scores_gemma":[0.9994602,0.0002396825,0.0001170473,0.00002825499,0.00008287648,0.00007204135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004673451,0.00002849784,0.000648975,0.00005763428,0.00001334535,0.00004074352,0.00002409829,0.00008590965,0.9976241,0.00002334301,0.00002441246,0.0009616017],"study_design_scores_gemma":[0.00001549171,0.0005455334,0.01240195,0.000008464249,0.00002175229,0.00009684815,0.00003627081,0.0005755083,0.9858641,0.00002510633,0.0003985861,0.00001034121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976764,0.0007333616,0.0004717134,0.00005396867,0.00001598617,0.00001082463,0.0001964784,0.00001904452,0.0008223195],"genre_scores_gemma":[0.9979802,0.0004644387,0.0006883087,0.00006055197,0.000008812751,0.00001038259,0.000287714,0.00001156891,0.000488081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008024563,"threshold_uncertainty_score":0.002684474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004003301568358161,"score_gpt":0.1557385319489841,"score_spread":0.151735230380626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}