{"id":"W2147279704","doi":"10.1038/embor.2012.32","title":"Early life antibiotic‐driven changes in microbiota enhance susceptibility to allergic asthma","year":2012,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":890,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Genome British Columbia","keywords":"Hygiene hypothesis; Asthma; Antibiotics; Immunology; Gut flora; Flora (microbiology); Population; Medicine; Disease; Vancomycin; Biology; Microbiology; Bacteria; Internal medicine; Staphylococcus aureus; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000208854,0.0002519001,0.0002943582,0.0002126315,0.0001345362,0.0005068982,0.0001218649,0.0006159756,0.001951739],"category_scores_gemma":[0.0005667647,0.0001929575,0.0002367971,0.0001158347,0.0002881932,0.0002550623,0.0003817143,0.001091456,0.0003325028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000235374,"about_ca_system_score_gemma":0.0001715388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003400926,"about_ca_topic_score_gemma":0.0008741079,"domain_scores_codex":[0.9997864,0.00005299373,0.00001089804,0.00003795289,0.00003790052,0.00007384148],"domain_scores_gemma":[0.999426,0.00008630333,0.0001755342,0.00005694807,0.00003499783,0.000220211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001244719,0.0002243647,0.01676232,0.00003540039,0.00002159831,0.0002180366,0.00004966111,0.00003718133,0.9757172,0.0001209653,0.000176719,0.00539183],"study_design_scores_gemma":[0.00006912878,0.002078033,0.8181065,0.00003619553,0.00007733872,0.0008825266,0.0004176897,0.0005857131,0.1746257,0.0004468914,0.002646591,0.00002773979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979487,0.0007101295,0.000424261,0.0002021739,0.00004613105,0.000008028784,0.0001166849,0.00002076598,0.000523135],"genre_scores_gemma":[0.9976529,0.0004746807,0.0003829971,0.0001207846,0.00002807838,0.00001030824,0.00009791591,0.00001207794,0.001220171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001951739,"threshold_uncertainty_score":0.006529152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090143966879989,"score_gpt":0.273999855324523,"score_spread":0.2630984156557231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}