{"id":"W2147304052","doi":"10.1016/j.thromres.2014.12.010","title":"Thrombin Generation Potential and Whole-Blood DNA methylation","year":2014,"lang":"en","type":"letter","venue":"Thrombosis Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"DNA methylation; Epigenetics; Genome-wide association study; Methylation; Promoter; Biology; Von Willebrand factor; Genetics; Gene; Missing heritability problem; Coagulation; Bioinformatics; Molecular biology; Gene expression; Medicine; Single-nucleotide polymorphism; Immunology; Internal medicine; Platelet; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007667087,0.0003753121,0.0005176619,0.0003317334,0.0005822686,0.001091966,0.0005680147,0.009132767,0.002823755],"category_scores_gemma":[0.004685303,0.0002209366,0.0004236725,0.0003186927,0.001102687,0.0009573313,0.0003645536,0.006101545,0.0009383355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009665696,"about_ca_system_score_gemma":0.000356016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005461107,"about_ca_topic_score_gemma":0.0006865796,"domain_scores_codex":[0.9995251,0.0001551913,0.0000383284,0.00008536167,0.0001362686,0.00005974558],"domain_scores_gemma":[0.9986511,0.001060281,0.0000716892,0.00007735588,0.00005757907,0.00008206988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003964812,0.0003614749,0.02387822,0.0004581387,0.0002840059,0.09722423,0.0006335294,0.001043663,0.03374873,0.04301048,0.5380835,0.2573092],"study_design_scores_gemma":[0.00129859,0.001516034,0.02475222,0.0003803007,0.0004917834,0.1182705,0.0007630502,0.008471655,0.0643924,0.1398916,0.6395769,0.0001949081],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.03634512,0.02073359,0.003823468,0.9030218,0.01648597,0.00004992726,0.0003169801,0.0001695424,0.01905368],"genre_scores_gemma":[0.576307,0.01612991,0.003550708,0.305973,0.07014467,0.0001841914,0.0002566402,0.0000545679,0.02739934],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009132767,"threshold_uncertainty_score":0.009446323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09797867137609356,"score_gpt":0.3686924283526988,"score_spread":0.2707137569766053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}