{"id":"W2147376659","doi":"10.1182/blood-2007-10-117820","title":"Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; BC Cancer Agency; Canadian Institutes of Health Research; Michael Smith Health Research BC; Stem Cell Network","keywords":"Haematopoiesis; Stem cell; Cell biology; Biology; Cell division; Transcription factor; Stem cell factor; Cell culture; Cellular differentiation; In vitro; In vivo; Hematopoietic stem cell; BMI1; CXCR4; Molecular biology; Immunology; Cell; Genetics; Gene; Chemokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000952124,0.0001421257,0.0002654698,0.00005280731,0.00006488591,0.000005328288,0.00006222829,0.0001494514,0.00004174063],"category_scores_gemma":[0.000007749207,0.00008921151,0.00006915932,0.0001500948,0.0001352843,0.00002944212,0.00001441331,0.0001396348,0.00001038773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006517126,"about_ca_system_score_gemma":0.00003285836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004415171,"about_ca_topic_score_gemma":4.567293e-7,"domain_scores_codex":[0.9991342,0.00006237005,0.0002437137,0.0002070956,0.0001977377,0.0001548662],"domain_scores_gemma":[0.9993986,0.0001245151,0.00009750063,0.0002405811,0.00007589809,0.00006284763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008757397,0.0002047938,0.007813446,0.0004344564,0.0001383257,0.00009987366,0.0009707783,0.000005022203,0.9894782,0.0004307815,0.00006011073,0.0002766676],"study_design_scores_gemma":[0.001871085,0.0003849367,0.03338848,0.0001334296,0.000314487,0.0005104827,0.0003087085,0.00001914184,0.9627172,0.0001002609,0.0001436829,0.0001080981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961167,0.002396832,0.0002716482,0.0001582602,0.00007275031,0.0004376376,0.00001352672,0.00004684737,0.0004858164],"genre_scores_gemma":[0.999154,0.0001881868,0.0001766916,0.00009992168,0.00002163142,0.00001120081,0.00000887876,0.00001653347,0.0003229436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02676096,"threshold_uncertainty_score":0.363794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01745226260838076,"score_gpt":0.2193808511439254,"score_spread":0.2019285885355446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}