{"id":"W2147376659","doi":"10.1182/blood-2007-10-117820","title":"Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; BC Cancer Agency; Canadian Institutes of Health Research; Michael Smith Health Research BC; Stem Cell Network","keywords":"Haematopoiesis; Stem cell; Cell biology; Biology; Cell division; Transcription factor; Stem cell factor; Cell culture; Cellular differentiation; In vitro; In vivo; Hematopoietic stem cell; BMI1; CXCR4; Molecular biology; Immunology; Cell; Genetics; Gene; Chemokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228975,0.0003436524,0.0002489955,0.0003085448,0.0001296851,0.0003128684,0.0001275885,0.0001714399,0.0007764199],"category_scores_gemma":[0.0001540564,0.0001285332,0.0001899308,0.0001419419,0.0001971096,0.0001605131,0.0001996421,0.0002631831,0.0003370333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341981,"about_ca_system_score_gemma":0.0001830766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006537545,"about_ca_topic_score_gemma":0.001324626,"domain_scores_codex":[0.9997926,0.00003807791,0.00002103436,0.00004203548,0.00005555912,0.00005070965],"domain_scores_gemma":[0.9998939,0.00001400437,0.00002705317,0.0000134399,0.00001920416,0.00003240711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000466551,0.000002669973,0.0003083392,0.000005950647,0.000001132954,0.00001805646,0.000006315834,0.00001735016,0.9990407,0.00002712305,0.00001370902,0.0005119584],"study_design_scores_gemma":[0.000008240947,0.0001642296,0.01968472,0.000002568473,0.00001194865,0.0001967704,0.00004029478,0.0006654955,0.9781541,0.00004821118,0.001019047,0.000004412424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956852,0.0009359351,0.001941879,0.00003384996,0.00001228836,0.00001629241,0.000316768,0.00007141375,0.0009864073],"genre_scores_gemma":[0.9953761,0.0003314201,0.001733723,0.00001917054,0.000009001759,0.00001529603,0.0005924451,0.00001967679,0.00190319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007764199,"threshold_uncertainty_score":0.002597332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01745226260838076,"score_gpt":0.2193808511439254,"score_spread":0.2019285885355446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}