{"id":"W2147443365","doi":"10.1161/circresaha.109.205310","title":"p53 Improves Aerobic Exercise Capacity and Augments Skeletal Muscle Mitochondrial DNA Content","year":2009,"lang":"en","type":"article","venue":"Circulation Research","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Skeletal muscle; Aerobic capacity; Mitochondrial DNA; Aerobic exercise; Mitochondrion; DNA; Exercise physiology; Cell biology; Biology; Chemistry; Endocrinology; Internal medicine; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001550838,0.0004550276,0.0003498589,0.0003997106,0.0001412249,0.0002224261,0.0002809758,0.0003364888,0.002541172],"category_scores_gemma":[0.000226078,0.00008927311,0.0002582146,0.0001619908,0.0003546268,0.0002906196,0.0002619732,0.000543147,0.0003006633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001590858,"about_ca_system_score_gemma":0.0001443757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001845516,"about_ca_topic_score_gemma":0.0003320185,"domain_scores_codex":[0.99991,0.00001324667,0.00001040551,0.00002375601,0.00002096204,0.00002159835],"domain_scores_gemma":[0.999862,0.00002445831,0.00004701217,0.00001282134,0.00001613234,0.00003773559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009545661,0.0003784703,0.001034868,0.0002413054,0.00002703323,0.00008983697,0.00001513,0.0001978717,0.984589,0.00008411665,0.0001591754,0.01222864],"study_design_scores_gemma":[0.0003354199,0.01330508,0.04570786,0.00009992596,0.0002290168,0.0007973363,0.00008295957,0.002380636,0.9323243,0.0004346215,0.004286457,0.00001629002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913374,0.003391023,0.002977187,0.000371097,0.00008451343,0.00005807016,0.0003068144,0.0002239649,0.001249987],"genre_scores_gemma":[0.9955639,0.001619285,0.00108889,0.00009904461,0.00003346604,0.0000562391,0.0002948787,0.00001797568,0.001226286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002541172,"threshold_uncertainty_score":0.008501112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06340367770397734,"score_gpt":0.3202470973109964,"score_spread":0.2568434196070191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}