{"id":"W2147449225","doi":"10.1128/jvi.78.13.7097-7111.2004","title":"Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak","year":2004,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Western University","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Moffitt Cancer Center; Cancer Research Institute","keywords":"Biology; HEK 293 cells; Transfection; Apoptosis; Cell biology; Poly ADP ribose polymerase; Cytochrome c; Embryonic stem cell; Molecular biology; Caspase; Polymerase; Receptor; Mitochondrion; Cell culture; Programmed cell death; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001351755,0.00019972,0.0001512284,0.0001080177,0.0001604032,0.0002904689,0.0001632069,0.0002014733,0.0006650894],"category_scores_gemma":[0.0001688787,0.0001033752,0.0001340607,0.00006353703,0.000196106,0.0001374183,0.0001851023,0.0004237535,0.0003588267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002660042,"about_ca_system_score_gemma":0.0001302974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002287674,"about_ca_topic_score_gemma":0.0003172319,"domain_scores_codex":[0.9998566,0.00004172531,0.00001578892,0.00001961083,0.00002970586,0.00003664268],"domain_scores_gemma":[0.9998887,0.00003035598,0.00003405799,0.0000171372,0.000009022576,0.00002067643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008410984,0.00004241009,0.0002045138,0.0000200816,0.000002594422,0.00002290584,0.00001122028,0.00002426238,0.9988674,0.00009641254,0.0000255805,0.0005985712],"study_design_scores_gemma":[0.00003363081,0.0005312056,0.002930329,0.000007125366,0.000009873466,0.0003377266,0.00002035624,0.0009088151,0.992608,0.00003210054,0.002578286,0.000002680383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976422,0.0007763059,0.0008261674,0.00005427179,0.000009518037,0.000008766846,0.00005762643,0.00002449212,0.0006006155],"genre_scores_gemma":[0.9975455,0.000282573,0.000801523,0.00002729797,0.000006744315,0.00001419657,0.0002801824,0.000007102881,0.001034839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006650894,"threshold_uncertainty_score":0.002224982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008914571541040276,"score_gpt":0.2555363618156352,"score_spread":0.2466217902745949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}