{"id":"W2147449225","doi":"10.1128/jvi.78.13.7097-7111.2004","title":"Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak","year":2004,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Western University","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Moffitt Cancer Center; Cancer Research Institute","keywords":"Biology; HEK 293 cells; Transfection; Apoptosis; Cell biology; Poly ADP ribose polymerase; Cytochrome c; Embryonic stem cell; Molecular biology; Caspase; Polymerase; Receptor; Mitochondrion; Cell culture; Programmed cell death; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009280609,0.00009581488,0.0001485298,0.00004133181,0.00005018978,0.0000087358,0.0000822255,0.0001336859,0.00002694627],"category_scores_gemma":[0.0000175011,0.00007011484,0.00007774286,0.00004250377,0.00008050053,0.00001320105,0.00002684483,0.0001171544,0.000004779312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002776604,"about_ca_system_score_gemma":0.00008337584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001679515,"about_ca_topic_score_gemma":0.00002088371,"domain_scores_codex":[0.9994012,0.00003901089,0.0002223469,0.0001215618,0.00009411357,0.0001218179],"domain_scores_gemma":[0.9994856,0.000006439457,0.0002753281,0.0001009494,0.00009005302,0.00004168892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000684631,0.0001425604,0.0001763776,0.00000552739,0.0001477895,0.00001583704,0.00009828563,0.002817728,0.9934129,0.0008241975,0.0001869843,0.001487235],"study_design_scores_gemma":[0.002348482,0.003310894,0.001667923,0.00004209577,0.00009527564,0.0008629705,0.0001099634,0.00001229169,0.9548708,0.002216046,0.03431699,0.00014622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9590613,0.0002657032,0.0390184,0.0003138864,0.0004011275,0.00007607769,0.000002640618,0.000002658154,0.0008582539],"genre_scores_gemma":[0.9963946,0.0003904426,0.002570572,0.0002753242,0.000246455,0.000002084919,0.000009194118,0.000009131604,0.0001021721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.038542,"threshold_uncertainty_score":0.28592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008914571541040276,"score_gpt":0.2555363618156352,"score_spread":0.2466217902745949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}