{"id":"W2147595513","doi":"10.1089/hum.2005.16.502","title":"Elements of Style: Consent Form Language and the Therapeutic Misconception in Phase 1 Gene Transfer Trials","year":2005,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Gene transfer; Clinical trial; Informed consent; Medicine; Genetic enhancement; Alternative medicine; Psychology; Intensive care medicine; Oncology; Gene; Internal medicine; Pathology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.008262863,0.0001248429,0.0005329035,0.00008807363,0.00006256554,0.00001507205,0.0001394511,0.0001373762,0.0009793597],"category_scores_gemma":[0.0004033254,0.0000744231,0.0001319359,0.00009636391,0.0004666509,0.0000331528,0.00001673973,0.0004747491,0.000006094966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004530217,"about_ca_system_score_gemma":0.0001206608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006924219,"about_ca_topic_score_gemma":0.0003395829,"domain_scores_codex":[0.9977334,0.0004952346,0.0008350814,0.0002186741,0.0004975097,0.0002200915],"domain_scores_gemma":[0.9967901,0.002588932,0.00009263279,0.0003679543,0.00009046165,0.00006988399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005503599,0.0008638153,0.0006587525,0.00006020402,0.0002561042,0.00001030742,0.01360794,0.00000178101,0.8570109,0.004071929,0.00004393942,0.1179107],"study_design_scores_gemma":[0.1667103,0.003357296,0.007478083,0.0002514629,0.0001653642,0.00002532606,0.002466341,0.0003155223,0.8008933,0.01579314,0.002233305,0.0003105637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98907,0.006261194,0.0001815725,0.002731957,0.00002654608,0.001215954,0.00001316789,0.00001303673,0.0004865752],"genre_scores_gemma":[0.9877977,0.009273017,0.0002610771,0.001599097,0.0002236213,0.00006146139,0.00001869441,0.00002044755,0.0007448453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1612067,"threshold_uncertainty_score":0.9999339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5530611944013699,"score_gpt":0.5986891459853254,"score_spread":0.04562795158395549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}