{"id":"W2147598859","doi":"10.1186/bcr2875","title":"Notch signaling as a therapeutic target for breast cancer treatment?","year":2011,"lang":"en","type":"review","venue":"Breast Cancer Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Alberta Cancer Foundation; Cancer Research Institute","keywords":"Notch signaling pathway; Breast cancer; Cancer research; Carcinogenesis; Hes3 signaling axis; Cancer; Signal transduction; Medicine; Biology; Bioinformatics; Receptor; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005073162,0.0004730082,0.0007536438,0.0001847193,0.0003066508,0.0000435148,0.000442367,0.0006766437,0.0008019999],"category_scores_gemma":[0.00000904896,0.0003565667,0.0004281038,0.0002901826,0.0002146941,0.000006438989,0.0001501716,0.0002456947,0.00008013574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003485512,"about_ca_system_score_gemma":0.002229525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006742938,"about_ca_topic_score_gemma":0.0001829688,"domain_scores_codex":[0.997383,0.0003300167,0.0003876025,0.0009010629,0.0002165323,0.0007817604],"domain_scores_gemma":[0.9988366,0.00005276759,0.0001637777,0.000435699,0.0003416439,0.0001695401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003679105,0.00009825636,0.0001038622,0.001301976,0.0008340746,0.000002287234,0.00003128831,0.000001815464,0.001837901,0.00005414804,0.0007230641,0.9946434],"study_design_scores_gemma":[0.0005120632,0.0002602705,0.0002220672,0.001269951,0.0002013519,0.0002072754,0.00001578706,0.000001585759,0.002099789,0.0001439089,0.9946225,0.0004434024],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003515908,0.9945817,0.00004255688,0.0001854293,0.0002937361,0.001636193,0.002540758,0.0000171905,0.0003508563],"genre_scores_gemma":[0.002121262,0.985788,0.0001078151,0.00005534234,0.001139321,0.003690525,0.001084017,0.0001025163,0.005911231],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942,"threshold_uncertainty_score":0.9998887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149258899700306,"score_gpt":0.4405393421290938,"score_spread":0.3256134521590632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}