{"id":"W2147598859","doi":"10.1186/bcr2875","title":"Notch signaling as a therapeutic target for breast cancer treatment?","year":2011,"lang":"en","type":"review","venue":"Breast Cancer Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Alberta Cancer Foundation; Cancer Research Institute","keywords":"Notch signaling pathway; Breast cancer; Cancer research; Carcinogenesis; Hes3 signaling axis; Cancer; Signal transduction; Medicine; Biology; Bioinformatics; Receptor; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000503014,0.0007570054,0.001341953,0.00123897,0.0002466167,0.0008976677,0.0009748529,0.00129288,0.004130608],"category_scores_gemma":[0.0003820061,0.0002781235,0.0003716082,0.001229114,0.0005081706,0.001604114,0.0005808665,0.002258914,0.004218922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006282547,"about_ca_system_score_gemma":0.0006447518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006915597,"about_ca_topic_score_gemma":0.00177669,"domain_scores_codex":[0.9998794,0.00002346738,0.00001654746,0.00002020673,0.00004714994,0.00001319143],"domain_scores_gemma":[0.9998851,0.00003620631,0.00001801624,0.00000626274,0.00003739961,0.00001700257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001217118,0.00008229054,0.0001176437,0.00861368,0.00007154751,0.0002791936,0.00004691399,0.0003545196,0.004469117,0.006233592,0.04709562,0.9325143],"study_design_scores_gemma":[0.00002594189,0.00007378467,0.0003017375,0.001572188,0.00004422542,0.001172713,0.00003491109,0.00006663963,0.0005202192,0.00213407,0.9940411,0.00001239635],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001265944,0.9973395,0.0001347404,0.0007238634,0.000329915,0.000004604746,0.00001822912,0.000008219735,0.001314147],"genre_scores_gemma":[0.0006913373,0.9968555,0.0002430257,0.0005993437,0.0002238958,0.0000079748,0.00003078871,0.000002398926,0.001345662],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004130608,"threshold_uncertainty_score":0.01381826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149258899700306,"score_gpt":0.4405393421290938,"score_spread":0.3256134521590632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}