{"id":"W2147603163","doi":"10.1196/annals.1317.049","title":"Identification of Proteins Regulated by PACAP in PC12 Cells by 2D Gel Electrophoresis Coupled to Mass Spectrometry","year":2006,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Armand Frappier Museum; Institut National de la Recherche Scientifique; Montreal Heart Institute","funders":"","keywords":"Hsp27; Heat shock protein; Gel electrophoresis; Two-dimensional gel electrophoresis; Calmodulin; Proteomics; Cell biology; HSP60; Cell culture; Tubulin; Adenylate kinase; Neurite; Molecular biology; Biology; Cellular differentiation; Chemistry; Biochemistry; Hsp70; Microtubule; Gene; In vitro; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002371618,0.0009590238,0.0008305807,0.001141529,0.000433073,0.0007147313,0.0004258328,0.0004840954,0.0006480162],"category_scores_gemma":[0.0002662204,0.0002496706,0.0004814287,0.001131239,0.0003249088,0.0003675429,0.00034471,0.0006657858,0.0008546583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004679595,"about_ca_system_score_gemma":0.0003793589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001664153,"about_ca_topic_score_gemma":0.002406406,"domain_scores_codex":[0.999763,0.00001678616,0.0000241608,0.00008911319,0.00007829362,0.00002860784],"domain_scores_gemma":[0.999869,0.00002592642,0.00003649082,0.00001133039,0.00003615491,0.00002113224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001002335,0.00001784802,0.0004374707,0.0001265738,0.00001372415,0.0001318151,0.00003565553,0.00004955339,0.996596,0.0000504346,0.00009684639,0.002343652],"study_design_scores_gemma":[0.00002319102,0.0001435497,0.04109771,0.00003372041,0.0001083529,0.001874634,0.000131528,0.002567199,0.9410126,0.0002119235,0.01275702,0.00003853339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9087033,0.01623643,0.05675143,0.0005605391,0.0002068174,0.0003091636,0.01213364,0.001088111,0.004010681],"genre_scores_gemma":[0.6886829,0.03518252,0.2326745,0.0008268915,0.0001477442,0.001465127,0.02770389,0.0005251876,0.01279121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001664153,"threshold_uncertainty_score":0.003395259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628639793113185,"score_gpt":0.2896170377929947,"score_spread":0.2533306398618629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}