{"id":"W2147620122","doi":"10.1002/cbic.201200442","title":"A Template‐Assembled Synthetic U‐Quadruplex","year":2012,"lang":"en","type":"article","venue":"ChemBioChem","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cavitand; Uracil; Uridine; G-quadruplex; Chemistry; Combinatorial chemistry; Nucleobase; Computer science; Stereochemistry; Computational biology; Biochemistry; Supramolecular chemistry; Biology; RNA; Organic chemistry; Molecule; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000164475,0.0002260027,0.0001662679,0.00002097881,0.00007921742,0.00002085689,0.0002654303,0.0002545973,0.0001944813],"category_scores_gemma":[0.00008776521,0.0002225616,0.0001360186,0.0000878342,0.00006222747,0.000006061613,0.0001568291,0.0001079953,0.0001921854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001996075,"about_ca_system_score_gemma":0.00003594388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000296099,"about_ca_topic_score_gemma":3.938355e-7,"domain_scores_codex":[0.9987905,0.00001563621,0.0001952482,0.0003264619,0.0001430797,0.0005290671],"domain_scores_gemma":[0.9990579,0.000009681286,0.00007219915,0.0005652859,0.00004568188,0.0002492549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003107566,0.000114741,0.002203063,0.00003117262,0.00004403167,0.000001363299,0.00004289538,4.000315e-7,0.9858043,0.00004925454,0.01098119,0.0006965196],"study_design_scores_gemma":[0.0003495291,0.00003063418,0.0004986802,0.00001168578,0.00002302009,0.00005846477,0.00008539693,0.000003979777,0.9119902,0.00001678743,0.08665344,0.0002782191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636691,0.001406667,0.0001316483,0.00009913905,0.0001984093,0.00008696487,0.000005751853,0.00004631921,0.03435601],"genre_scores_gemma":[0.9947201,0.00005877871,0.0004975146,0.0002705137,0.0007239574,0.00002832715,0.00009008627,0.00004643861,0.003564296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07567225,"threshold_uncertainty_score":0.9075799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009775027916547588,"score_gpt":0.2393941816834268,"score_spread":0.2296191537668792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}