{"id":"W2147620122","doi":"10.1002/cbic.201200442","title":"A Template‐Assembled Synthetic U‐Quadruplex","year":2012,"lang":"en","type":"article","venue":"ChemBioChem","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cavitand; Uracil; Uridine; G-quadruplex; Chemistry; Combinatorial chemistry; Nucleobase; Computer science; Stereochemistry; Computational biology; Biochemistry; Supramolecular chemistry; Biology; RNA; Organic chemistry; Molecule; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707692,0.0002716481,0.0003019932,0.000146941,0.0001828015,0.0003053993,0.0003691574,0.0004881698,0.001736364],"category_scores_gemma":[0.0002353238,0.0002017041,0.0001638776,0.000152183,0.0001186714,0.0002167951,0.000149853,0.0003482885,0.001215004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002647051,"about_ca_system_score_gemma":0.0001804628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002432071,"about_ca_topic_score_gemma":0.0004284826,"domain_scores_codex":[0.9998615,0.00001557344,0.00001055202,0.00005686561,0.00003444032,0.00002106142],"domain_scores_gemma":[0.9999307,0.00001031095,0.00001614707,0.000009507301,0.00001092625,0.00002236809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003223458,0.0000247314,0.00004376517,0.00004181502,0.000003863337,0.00003662692,0.00001435246,0.0001452366,0.9970865,0.0001971467,0.00008291116,0.002290876],"study_design_scores_gemma":[0.00001205584,0.000242072,0.0002127479,0.000003072932,0.000007274327,0.000127486,0.000006327921,0.0008737543,0.9936748,0.00003919256,0.004792278,0.000008906914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519757,0.001506549,0.03525166,0.000153784,0.0001582871,0.0003757886,0.001435836,0.001210189,0.007932192],"genre_scores_gemma":[0.9514648,0.0005734658,0.03601282,0.0001239095,0.00002541883,0.0001531414,0.001574201,0.0001312847,0.009941008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736364,"threshold_uncertainty_score":0.005808771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009775027916547588,"score_gpt":0.2393941816834268,"score_spread":0.2296191537668792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}