{"id":"W2147649225","doi":"10.4161/cbt.29822","title":"HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion","year":2014,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Motility; Hypoxia (environmental); Cell biology; Cytosol; Ubiquitin ligase; Subcellular localization; Biology; Cancer research; Tyrosine kinase; Cancer cell; Ubiquitin; Chemistry; Signal transduction; Cancer; Cytoplasm; Biochemistry; Gene; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004185908,0.0002732114,0.000345553,0.00005377634,0.0001511987,0.00002140238,0.0001744616,0.0003776744,0.0001261917],"category_scores_gemma":[0.00008438805,0.000217351,0.00007517944,0.0001377882,0.0001798399,0.000006677002,0.00005606058,0.0001399096,0.000002083276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004592028,"about_ca_system_score_gemma":0.0001769365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003464757,"about_ca_topic_score_gemma":0.0005604431,"domain_scores_codex":[0.9983352,0.000304701,0.0002349705,0.0006637849,0.000115429,0.000345953],"domain_scores_gemma":[0.9990305,0.00003713827,0.0001792651,0.000433115,0.0001822634,0.0001376862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004269862,0.00008946276,0.02704932,0.000007295411,0.0001809109,2.062392e-7,0.0001490869,0.000004268711,0.9101072,0.00003101523,0.000491995,0.06146227],"study_design_scores_gemma":[0.007003928,0.0016504,0.2567034,0.00003909982,0.00008502647,0.000009341307,0.00007911512,0.0001192607,0.6131158,0.0004292981,0.1201559,0.0006093367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907887,0.007377013,0.00036663,0.000244908,0.000556469,0.0003907759,0.00007465788,0.00003256558,0.0001682803],"genre_scores_gemma":[0.9889202,0.007768238,0.00005074756,0.002113661,0.0006999124,0.00009199465,0.00023239,0.00003499565,0.00008787731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2969913,"threshold_uncertainty_score":0.8863316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990108198400801,"score_gpt":0.2599245646669595,"score_spread":0.2400234826829515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}