{"id":"W2147701170","doi":"10.1002/etc.5620190323","title":"Dose-dependent stimulation of hepatic retinoic acid hydroxylation/oxidation and glucuronidation in brook trout,<i>Salvelinus fontinalis</i>, after exposure to 3,3′,4,4′-tetrachlorobiphenyl","year":2000,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Salvelinus; Glucuronidation; Fontinalis; Trout; Hydroxylation; Stimulation; Chemistry; Retinoic acid; Internal medicine; Endocrinology; Biology; Biochemistry; Fish <Actinopterygii>; Fishery; Microsome; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001292931,0.0003772261,0.0002276538,0.0003645067,0.0002174907,0.0002822641,0.0001270673,0.0002398318,0.001197955],"category_scores_gemma":[0.00019487,0.0002401906,0.0002764809,0.0001528692,0.0003811823,0.0001775514,0.0002170664,0.0004191601,0.0003587045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005504655,"about_ca_system_score_gemma":0.0003275952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006252833,"about_ca_topic_score_gemma":0.01076326,"domain_scores_codex":[0.9998773,0.00001751655,0.00001016091,0.00004431084,0.00002606709,0.00002455952],"domain_scores_gemma":[0.9997172,0.00003366422,0.00008286902,0.00002923438,0.00005215887,0.00008485556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003372611,0.0000175595,0.001546536,0.00001393359,0.000006584826,0.00002612817,0.00003964317,0.00002631573,0.9975936,0.00001055679,0.00001846922,0.000363494],"study_design_scores_gemma":[0.00005582958,0.002637366,0.09917838,0.00000681299,0.00005301453,0.0001949553,0.0002003279,0.0006313798,0.8959169,0.00004074017,0.001064406,0.00001994817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989426,0.0001403311,0.0002447517,0.00002885169,0.000007193997,0.000009296593,0.0002403424,0.00002932779,0.0003573584],"genre_scores_gemma":[0.9943908,0.0001942817,0.0007671508,0.00004263167,0.000006858331,0.00004731265,0.0008301479,0.00002264062,0.003698068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006252833,"threshold_uncertainty_score":0.01243287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00255801419303735,"score_gpt":0.1935843926640654,"score_spread":0.191026378471028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}