{"id":"W2147719235","doi":"10.1039/c5ra08612d","title":"Analyzing the effects of protecting osmolytes on solute–water interactions by solvatochromic comparison method: II. Globular proteins","year":2015,"lang":"en","type":"article","venue":"RSC Advances","topic":"Chemical and Physical Properties in Aqueous Solutions","field":"Chemical Engineering","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Russian Science Foundation","keywords":"Globular protein; Chemistry; Osmolyte; Sodium; Globular cluster; Sorbitol; Aqueous solution; Potassium phosphate; Phosphate buffered saline; Potassium; Chromatography; PEG ratio; Solvatochromism; Biochemistry; Organic chemistry; Solvent","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001826147,0.0001935827,0.0003085254,0.00002789724,0.000264794,0.0000187051,0.0002714761,0.00005632338,0.00002138561],"category_scores_gemma":[0.0006581243,0.0001126793,0.0001169097,0.0001582484,0.0001065146,0.0001686756,0.0001763075,0.0005335902,0.00002329308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001126274,"about_ca_system_score_gemma":0.00001315778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001024801,"about_ca_topic_score_gemma":0.000004966428,"domain_scores_codex":[0.9988138,0.000084825,0.0003205413,0.0002546512,0.0002014695,0.0003246864],"domain_scores_gemma":[0.998969,0.0004817224,0.0001043856,0.0002766832,0.000071582,0.00009667373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000479907,0.0002092918,0.0000255371,0.000168819,0.00006339099,6.272472e-7,0.0007290377,0.00882431,0.9828712,0.0003667157,0.0007253113,0.005967721],"study_design_scores_gemma":[0.0002623528,0.0001627839,0.000001054538,0.0002037942,0.00003501262,0.000002239537,0.00009885045,0.03545,0.9481083,0.002298185,0.01320327,0.0001741709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5561767,0.006069967,0.4292105,0.001399421,0.000770705,0.001758103,0.00002852143,0.0004756736,0.004110426],"genre_scores_gemma":[0.994002,0.00001081277,0.005183836,0.00003855259,0.0001748466,0.0001636439,0.00001123355,0.00002478908,0.0003903256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4378253,"threshold_uncertainty_score":0.4594927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01918333811026349,"score_gpt":0.2938180554130189,"score_spread":0.2746347173027555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}