{"id":"W2147750581","doi":"10.1161/01.res.0000137173.42723.fb","title":"Preferential Expression and Function of Voltage-Gated, O <sub>2</sub> -Sensitive K <sup>+</sup> Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction","year":2004,"lang":"en","type":"article","venue":"Circulation Research","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; St. Stephen's University; University of Calgary; University of Alberta Hospital; University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heritage Medical Research Institute; Heart and Stroke Foundation of Canada","keywords":"Hypoxic pulmonary vasoconstriction; Vasoconstriction; Hypoxia (environmental); Cardiology; Internal medicine; Vascular resistance; Chemistry; Oxygen; Medicine; Hemodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009354658,0.0001398311,0.0002132555,0.0001999639,0.00007760149,0.0002453604,0.0001492862,0.0001746502,0.0005831145],"category_scores_gemma":[0.0001397806,0.0001692664,0.0001567954,0.00008531639,0.000237881,0.0003019719,0.0001593791,0.0002676287,0.0001927482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001454992,"about_ca_system_score_gemma":0.00006795034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000341517,"about_ca_topic_score_gemma":0.0004164397,"domain_scores_codex":[0.9999202,0.00000681258,0.000006981748,0.00003284782,0.000009583056,0.00002357201],"domain_scores_gemma":[0.9998307,0.00001657325,0.00007925952,0.00001961298,0.00001536071,0.00003847338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002412714,0.00001372996,0.004718946,0.00001569563,0.000005554577,0.00008785307,0.00002445791,0.0000263476,0.9935399,0.0000605749,0.00001653157,0.001249144],"study_design_scores_gemma":[0.00002823659,0.0005888606,0.6006287,0.00000798442,0.0000714634,0.00199526,0.0001941797,0.001249794,0.3941251,0.0003103314,0.0007889007,0.0000111461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978702,0.0005082191,0.001244022,0.0000295458,0.000002640412,0.000003470276,0.00006323062,0.00002061636,0.0002581924],"genre_scores_gemma":[0.9990221,0.0002285273,0.0003534757,0.00001685366,0.000008088169,0.000005848218,0.00008792751,0.000006164802,0.0002710412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005831145,"threshold_uncertainty_score":0.001950681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03843883886992764,"score_gpt":0.2776824508258383,"score_spread":0.2392436119559107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}