{"id":"W2147750581","doi":"10.1161/01.res.0000137173.42723.fb","title":"Preferential Expression and Function of Voltage-Gated, O <sub>2</sub> -Sensitive K <sup>+</sup> Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction","year":2004,"lang":"en","type":"article","venue":"Circulation Research","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; St. Stephen's University; University of Calgary; University of Alberta Hospital; University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heritage Medical Research Institute; Heart and Stroke Foundation of Canada","keywords":"Hypoxic pulmonary vasoconstriction; Vasoconstriction; Hypoxia (environmental); Cardiology; Internal medicine; Vascular resistance; Chemistry; Oxygen; Medicine; Hemodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006624053,0.0001735649,0.0001844804,0.0005240077,0.0001727499,0.0000330331,0.00007402379,0.0003116476,0.000006175408],"category_scores_gemma":[0.0001079171,0.0001908608,0.0000653735,0.0005399217,0.0002184699,0.00006241501,0.00008302316,0.0002512522,0.000004246753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001251926,"about_ca_system_score_gemma":0.000115752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003971906,"about_ca_topic_score_gemma":0.00007914663,"domain_scores_codex":[0.9979205,0.0003251189,0.0004144983,0.0005675447,0.0004485391,0.000323771],"domain_scores_gemma":[0.9991911,0.00004562699,0.0001136248,0.0002413413,0.0003204221,0.00008785319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008258663,0.0002042282,0.008603191,0.00006830844,0.00001348938,0.000009193178,0.0002387601,0.05575033,0.9306342,0.0001254875,0.00004556378,0.003481359],"study_design_scores_gemma":[0.001885091,0.00021091,0.2009782,0.0002908,0.000009162336,0.0000429807,0.001198607,0.01770163,0.7752971,0.001604663,0.0004420544,0.0003388252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915963,0.0002781058,0.00714625,0.0001151153,0.0001349238,0.0005331231,0.000014083,0.00001566849,0.000166419],"genre_scores_gemma":[0.9988268,0.0002855744,0.00003432109,0.00002158879,0.0002391971,0.00007125359,0.0004613486,0.00002185949,0.00003803526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.192375,"threshold_uncertainty_score":0.7783077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03843883886992764,"score_gpt":0.2776824508258383,"score_spread":0.2392436119559107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}