{"id":"W2147785262","doi":"10.1128/jvi.75.2.1072-1076.2001","title":"The vhs1 Mutant Form of Herpes Simplex Virus Virion Host Shutoff Protein Retains Significant Internal Ribosome Entry Site-Directed RNA Cleavage Activity","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Endoribonuclease; Biology; Herpes simplex virus; RNA; Internal ribosome entry site; Virus; Virology; Molecular biology; Protein biosynthesis; Transfection; Mutant; Messenger RNA; Cleavage (geology); Ribosome; Cell biology; Cell culture; Biochemistry; Gene; RNase P; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001284941,0.0003593329,0.0002926144,0.0001411978,0.0001441071,0.0003677772,0.0002136024,0.0002282199,0.001343081],"category_scores_gemma":[0.0001959338,0.0001029298,0.0002647962,0.0001409987,0.0003684459,0.0001560874,0.0001352405,0.0003990147,0.0005403435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003934569,"about_ca_system_score_gemma":0.0002179453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003977843,"about_ca_topic_score_gemma":0.0003837389,"domain_scores_codex":[0.9998794,0.00001989069,0.0000149721,0.0000241407,0.00003797376,0.00002352272],"domain_scores_gemma":[0.9998234,0.00003868457,0.00005762946,0.00002699524,0.00001314495,0.00004016847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073363,0.00002235287,0.0003804974,0.00002168639,0.000006037137,0.00007392198,0.00001105024,0.00007949684,0.9980349,0.0002333765,0.00003002422,0.0009993934],"study_design_scores_gemma":[0.00001178559,0.0002080157,0.002745322,0.000003895269,0.0000106051,0.0006912746,0.00001876099,0.0007562574,0.993174,0.00006508207,0.002309751,0.000005122261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976999,0.0004134118,0.001141656,0.00003344888,0.00001973407,0.000006648962,0.0001857068,0.00003549749,0.0004639299],"genre_scores_gemma":[0.9964705,0.0002013563,0.0009344819,0.00001380564,0.000007667461,0.000007514886,0.0007822186,0.0000230493,0.001559327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001343081,"threshold_uncertainty_score":0.004492998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01499814268084676,"score_gpt":0.2825268980356808,"score_spread":0.267528755354834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}