{"id":"W2147791685","doi":"10.1126/scitranslmed.3001327","title":"Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension","year":2010,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":254,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Alberta","funders":"","keywords":"Hypoxic pulmonary vasoconstriction; Pulmonary hypertension; Hypoxia (environmental); Beta oxidation; Medicine; Internal medicine; NFAT; Endocrinology; Pulmonary artery; Vasoconstriction; Calcineurin; Metabolism; Chemistry; Transplantation; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001390815,0.0001100075,0.0002161541,0.0003321548,0.0001453654,0.000006747024,0.0001475711,0.00004496169,0.0000519783],"category_scores_gemma":[0.0003544688,0.00006199122,0.00003572675,0.0007388899,0.000894407,0.0002199055,0.00001607371,0.0002636538,0.000002991913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001035001,"about_ca_system_score_gemma":0.0001829445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001209271,"about_ca_topic_score_gemma":0.00002611501,"domain_scores_codex":[0.9979864,0.00004106826,0.0002722876,0.0003026438,0.001168602,0.0002289447],"domain_scores_gemma":[0.9991229,0.0001548399,0.00004393415,0.0002714955,0.0002489592,0.0001578662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001181179,0.0001818748,0.0405276,0.00002675766,0.000007282591,0.0001654919,0.0001656376,0.00001015051,0.9458019,0.0003972266,0.000006431044,0.01259155],"study_design_scores_gemma":[0.00202855,0.0002107868,0.9451261,0.0001798444,0.00006429877,0.0008607848,0.0002814423,0.03760996,0.01160127,0.001823693,0.0001259118,0.00008740204],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880899,0.0006813454,0.0002948139,0.009632234,0.00008357022,0.0003805697,0.000002863487,0.00001023495,0.000824466],"genre_scores_gemma":[0.9969723,0.0001507116,0.002335729,0.0004172367,0.00006758611,0.00001027726,0.00003205769,0.000005980259,0.000008079096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9342006,"threshold_uncertainty_score":0.329548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03528876744071222,"score_gpt":0.3078289271767987,"score_spread":0.2725401597360864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}