{"id":"W2147808471","doi":"10.1016/j.ygyno.2006.03.017","title":"Gemcitabine and oxaliplatin followed by paclitaxel and carboplatin as first line therapy for patients with suboptimally debulked, advanced epithelial ovarian cancer. A phase II trial of sequential doublets. The GO-First Study","year":2006,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Thomas Hospital","funders":"Sanofi; Eli Lilly and Company","keywords":"Medicine; Oxaliplatin; Gemcitabine; Carboplatin; Internal medicine; Ovarian cancer; Regimen; Neutropenia; Chemotherapy; Phases of clinical research; Nausea; Gastroenterology; Debulking; Urology; Paclitaxel; Oncology; Surgery; Cancer; Cisplatin; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001052718,0.00104089,0.002128571,0.0007210064,0.000321741,0.0008520436,0.0007564588,0.001458664,0.0028146],"category_scores_gemma":[0.001394941,0.000519436,0.001152963,0.0007618709,0.0007586689,0.001100335,0.0004881158,0.003172582,0.0004295957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001088291,"about_ca_system_score_gemma":0.001614256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00199873,"about_ca_topic_score_gemma":0.009663099,"domain_scores_codex":[0.9996774,0.0001771403,0.00001145112,0.00003349093,0.00003181383,0.00006870268],"domain_scores_gemma":[0.9992474,0.0001526104,0.0001178522,0.00003708434,0.00001767179,0.0004274885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.866454,0.01153536,0.005943915,0.0009904904,0.001887634,0.0002445744,0.0002601669,0.002871004,0.006060232,0.0004578453,0.006811104,0.0964838],"study_design_scores_gemma":[0.7834249,0.1853169,0.01952013,0.0001597449,0.001503675,0.0004439681,0.0001695853,0.001486807,0.001716195,0.0004460787,0.00576814,0.00004394413],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880046,0.007721241,0.0001220212,0.00110495,0.0002251384,0.0004061076,0.0004197019,0.00007734587,0.001918828],"genre_scores_gemma":[0.9898606,0.004304092,0.0007687328,0.001332837,0.000223197,0.0005229252,0.001213567,0.00002300442,0.001751088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0028146,"threshold_uncertainty_score":0.009415746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594491450958239,"score_gpt":0.313273242588668,"score_spread":0.2973283280790856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}