{"id":"W2147858869","doi":"10.1261/rna.2112705","title":"Functional characterization of the SOFA<i>delta</i>ribozyme","year":2005,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Ribozyme; Hairpin ribozyme; Mammalian CPEB3 ribozyme; VS ribozyme; Adapter (computing); Biology; Riboswitch; RNase P; Ligase ribozyme; Computational biology; Directed evolution; Cleavage (geology); RNA; Biophysics; Genetics; Mutant; Gene; Computer science; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007400924,0.0000533805,0.00004793788,0.000008685308,0.00004298629,0.000005197889,0.00009489886,0.00005850825,0.0001171294],"category_scores_gemma":[0.00001901724,0.00003870779,0.00005630605,0.00003532506,0.0000207727,0.000002280227,0.00003619473,0.0000242059,0.00001663069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003862631,"about_ca_system_score_gemma":0.00002420195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001741613,"about_ca_topic_score_gemma":0.000002710262,"domain_scores_codex":[0.9996152,0.000026517,0.00009703515,0.0001008158,0.00008605413,0.00007437152],"domain_scores_gemma":[0.9997043,0.00000216004,0.00006139707,0.0001816281,0.00003289451,0.00001762278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001719171,0.00001691652,0.0001251283,0.000003162315,0.000008931867,3.916572e-8,0.000008207528,0.00001131404,0.9878208,0.0002587699,0.0003717965,0.01135776],"study_design_scores_gemma":[0.00007658356,0.00002300387,0.005089875,0.000005482154,0.000005201575,0.000002455881,0.000002897423,0.00001720993,0.940069,0.00004822529,0.05461361,0.00004641071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916178,0.00008588878,0.006389301,0.0005970745,0.0001683533,0.0000912146,0.00001885395,0.000005077845,0.001026451],"genre_scores_gemma":[0.9967278,0.00003202047,0.0002206471,0.00035028,0.0003384622,0.000008852637,0.00004822075,0.000007777436,0.002265988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05424181,"threshold_uncertainty_score":0.1578458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009219279794282489,"score_gpt":0.2024429938905607,"score_spread":0.1932237140962782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}