{"id":"W2147859611","doi":"10.2174/092986709789712899","title":"Pituitary Adenylate Cyclase-Activating Polypeptide: Focus on Structure- Activity Relationships of a Neuroprotective Peptide","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Agence Nationale de la Recherche; Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Neuroprotection; Receptor; Pituitary adenylate cyclase-activating peptide; Adenylate kinase; Pharmacology; Chemistry; In vivo; Peptide; Cyclase; Neuropeptide; Neuroscience; Cell biology; Biochemistry; Biology; Vasoactive intestinal peptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002387069,0.0007927918,0.0008699744,0.0009978679,0.0001898872,0.0005178598,0.0005342652,0.0006299846,0.002378499],"category_scores_gemma":[0.0001662484,0.0002366987,0.0002636435,0.001516151,0.0003231243,0.0009607326,0.0003454871,0.001062119,0.002558734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005511267,"about_ca_system_score_gemma":0.0004756049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005113407,"about_ca_topic_score_gemma":0.00066149,"domain_scores_codex":[0.9999324,0.000008208037,0.000008588981,0.00001807114,0.00002508854,0.000007693109],"domain_scores_gemma":[0.9999324,0.00002149338,0.00001348768,0.00000299543,0.00001957792,0.00001006414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001493773,0.0002353821,0.0001753607,0.01451288,0.00006229229,0.0008746305,0.00009059447,0.001287102,0.05888486,0.008427665,0.01465976,0.9006401],"study_design_scores_gemma":[0.00004290848,0.0003540429,0.001232497,0.001047422,0.00008394312,0.003147942,0.00005519129,0.0003128374,0.01217013,0.003116438,0.9784099,0.00002671611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001019091,0.9940508,0.0006899401,0.0001775947,0.0001582042,0.000009520836,0.00002770984,0.00001311457,0.003854093],"genre_scores_gemma":[0.004193045,0.9918405,0.001019823,0.000181871,0.0002024081,0.00001459676,0.00006725466,0.000003319429,0.002477251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002378499,"threshold_uncertainty_score":0.007956862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1262111272593446,"score_gpt":0.3543711271224261,"score_spread":0.2281599998630815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}