{"id":"W2147937741","doi":"10.1586/14737159.6.4.597","title":"Current and future molecular diagnostics for prion diseases","year":2006,"lang":"en","type":"article","venue":"Expert Review of Molecular Diagnostics","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital; Amorfix (Canada)","funders":"","keywords":"Bovine spongiform encephalopathy; Chronic wasting disease; Disease; Prion protein; Virology; Biology; Transmissible spongiform encephalopathy; Medicine; Scrapie; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001477235,0.0003123653,0.0003944735,0.00004478898,0.00007525476,0.00002678175,0.0002405256,0.0001214085,0.00001601768],"category_scores_gemma":[0.001042049,0.0002954582,0.0003147112,0.0001142112,0.00009400659,0.000006295772,0.0001662608,0.00007852459,0.000001823448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001480289,"about_ca_system_score_gemma":0.00009472417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007601555,"about_ca_topic_score_gemma":0.000001215221,"domain_scores_codex":[0.9983823,0.00009770982,0.0004701688,0.000474267,0.0002609255,0.0003146733],"domain_scores_gemma":[0.9987439,0.0001056676,0.0002218071,0.000519327,0.0002403878,0.0001689187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001260972,0.001118249,0.004572071,0.01409195,0.0002445835,0.00008430144,0.00002654719,0.00004732214,0.1863985,0.01363281,0.1415164,0.6381412],"study_design_scores_gemma":[0.0006845524,0.0002697911,0.001023201,0.0025877,0.0002294036,0.00001052349,0.000008992396,0.00002054407,0.1043045,0.001007864,0.8893553,0.0004976944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0176123,0.9525849,0.02741487,0.0007120767,0.0003019801,0.001110067,0.0002141653,0.00001708795,0.00003259227],"genre_scores_gemma":[0.03296535,0.9585792,0.004923681,0.001506956,0.0007829619,0.000321945,0.0008600982,0.00005626401,0.000003538352],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7478389,"threshold_uncertainty_score":0.9999498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004820589439407899,"score_gpt":0.2845613551774369,"score_spread":0.279740765738029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}