{"id":"W2147937741","doi":"10.1586/14737159.6.4.597","title":"Current and future molecular diagnostics for prion diseases","year":2006,"lang":"en","type":"article","venue":"Expert Review of Molecular Diagnostics","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital; Amorfix (Canada)","funders":"","keywords":"Bovine spongiform encephalopathy; Chronic wasting disease; Disease; Prion protein; Virology; Biology; Transmissible spongiform encephalopathy; Medicine; Scrapie; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002259689,0.0007974188,0.0006975929,0.001176864,0.0003310829,0.001407391,0.0009475807,0.002808086,0.006420472],"category_scores_gemma":[0.0008460634,0.000344643,0.0003719,0.000553305,0.001149468,0.002604065,0.0004722885,0.001720005,0.003262369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008460641,"about_ca_system_score_gemma":0.0008610225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003348734,"about_ca_topic_score_gemma":0.0006811912,"domain_scores_codex":[0.9993863,0.0001671282,0.00003283147,0.00007420266,0.000287081,0.00005228427],"domain_scores_gemma":[0.9995416,0.0001676751,0.00006377767,0.00002367801,0.0001227959,0.00008045915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000290048,0.0003591219,0.0009085551,0.00347901,0.00005418066,0.000871514,0.0002184822,0.0008858286,0.1475755,0.04158175,0.03728301,0.766493],"study_design_scores_gemma":[0.0001060676,0.0007617193,0.001563805,0.0007217153,0.00007915776,0.0037406,0.0002467715,0.001959991,0.03386379,0.02638383,0.9305041,0.00006835334],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004112089,0.9431139,0.0252223,0.01143285,0.001412789,0.00007720599,0.00009591311,0.0002681902,0.01426463],"genre_scores_gemma":[0.03600301,0.8872964,0.04842797,0.006198906,0.002457983,0.0001723574,0.000234934,0.00003371573,0.0191748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006420472,"threshold_uncertainty_score":0.02147859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004820589439407899,"score_gpt":0.2845613551774369,"score_spread":0.279740765738029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}