{"id":"W2147966783","doi":"10.1038/emboj.2008.21","title":"TLC1 RNA nucleo‐cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cegep Edouard Montpetit; Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Telomere; Telomerase; Telomerase RNA component; RNA; Cell biology; Cytoplasm; Biogenesis; Telomerase reverse transcriptase; Molecular biology; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008382956,0.0004961097,0.0007297085,0.0006506062,0.001131365,0.0001160398,0.000669923,0.000200416,0.0007145235],"category_scores_gemma":[0.0003929317,0.00033979,0.0003495911,0.001112125,0.0001306428,0.0001809739,0.0001623129,0.001122262,0.001262085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003296038,"about_ca_system_score_gemma":0.0004060082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004239015,"about_ca_topic_score_gemma":0.00002905899,"domain_scores_codex":[0.9963046,0.0002032185,0.000883382,0.000535174,0.001044876,0.001028778],"domain_scores_gemma":[0.997221,0.0002111457,0.0002346329,0.0007144565,0.0003400009,0.001278789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003526645,0.001509681,0.01457827,0.000189517,0.001061922,0.006800053,0.03088365,0.001781872,0.4066081,0.0001967829,0.1152493,0.4176141],"study_design_scores_gemma":[0.006707288,0.00367221,0.1849621,0.001732804,0.0007812313,0.03898589,0.004399373,0.0004243573,0.4099151,0.0001452288,0.3459164,0.002357999],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808039,0.001542897,0.0002350896,0.01370296,0.001042649,0.00120851,0.00002203516,0.0001715255,0.00127045],"genre_scores_gemma":[0.9838595,0.001592905,0.002199539,0.008225776,0.001658996,0.00005612951,0.000005718799,0.0001053005,0.002296115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4152561,"threshold_uncertainty_score":0.9999054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09612448480436854,"score_gpt":0.3167601810873211,"score_spread":0.2206356962829525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}