{"id":"W2147966783","doi":"10.1038/emboj.2008.21","title":"TLC1 RNA nucleo‐cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cegep Edouard Montpetit; Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Telomere; Telomerase; Telomerase RNA component; RNA; Cell biology; Cytoplasm; Biogenesis; Telomerase reverse transcriptase; Molecular biology; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002301751,0.0003278333,0.0003167073,0.0003174192,0.0006233928,0.00127794,0.0003971366,0.0006026921,0.004170603],"category_scores_gemma":[0.0005495687,0.000302134,0.0002832445,0.0001923252,0.0005548627,0.0006270378,0.0005981711,0.0008830164,0.001926957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008433657,"about_ca_system_score_gemma":0.0005155936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007652704,"about_ca_topic_score_gemma":0.001306925,"domain_scores_codex":[0.9998815,0.0000138816,0.000008090442,0.00004127981,0.00002313372,0.00003212175],"domain_scores_gemma":[0.9997413,0.00005891271,0.00004606993,0.00003781483,0.000037184,0.00007866531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008546606,0.00002948826,0.0007731612,0.0001300014,0.00001264733,0.0002177232,0.00007475427,0.000274252,0.9882257,0.001816214,0.001101676,0.006489792],"study_design_scores_gemma":[0.00006473175,0.0001146917,0.0103449,0.00003041442,0.00002996284,0.0004451968,0.0001392716,0.002956712,0.9747276,0.0008658895,0.01025975,0.00002090867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9664561,0.01141453,0.008363014,0.001868842,0.0002475638,0.00001705148,0.0007579103,0.0007425435,0.01013246],"genre_scores_gemma":[0.9891303,0.001370796,0.001364344,0.0001475116,0.00005335,0.0000169106,0.0006373822,0.00009180207,0.007187713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004170603,"threshold_uncertainty_score":0.01395202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09612448480436854,"score_gpt":0.3167601810873211,"score_spread":0.2206356962829525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}