{"id":"W2147994732","doi":"10.1097/00002030-200005050-00002","title":"Accelerated replicative senescence of the peripheral immune system induced by HIV infection","year":2000,"lang":"en","type":"article","venue":"AIDS","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Heritage Medical Research Clinic; Health Sciences Centre","funders":"Medical Research Council","keywords":"Telomere; Telomerase; Peripheral blood mononuclear cell; CD8; Immunology; Biology; Immune system; Senescence; Antibody; Telomerase reverse transcriptase; Virology; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001551141,0.000150681,0.0003018,0.0000404512,0.0001154536,0.00001320769,0.0001379905,0.0001078888,0.0002843038],"category_scores_gemma":[0.00004864123,0.0001038857,0.0001024865,0.000591649,0.00009656214,0.00009844475,0.00002532323,0.0002129003,0.00004341747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001121698,"about_ca_system_score_gemma":0.00008342775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006939318,"about_ca_topic_score_gemma":0.000003814515,"domain_scores_codex":[0.99884,0.0001066264,0.0003416768,0.0002683697,0.0002395768,0.0002037909],"domain_scores_gemma":[0.9990466,0.0000297742,0.0001213378,0.0005966561,0.0001350401,0.00007056823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002259307,0.0001839241,0.09195083,0.0001542681,0.00007973144,0.000004820289,0.0008534023,0.000004870115,0.8655691,0.0001985535,0.0007299096,0.04004471],"study_design_scores_gemma":[0.001216221,0.0004282175,0.4399169,0.0003852519,0.00007942437,0.00008606073,0.0003373906,0.0002981782,0.5534817,0.000005535163,0.003570016,0.0001950787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949656,0.0002506589,0.00005013109,0.0002938125,0.0001348667,0.000369842,0.00001026241,0.0001078709,0.003816938],"genre_scores_gemma":[0.9965273,0.00007159555,0.0000654578,0.0001331291,0.00006758882,0.00002434221,0.00001687337,0.0000189433,0.003074772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3479661,"threshold_uncertainty_score":0.4236337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01761130609724737,"score_gpt":0.2596857326707042,"score_spread":0.2420744265734568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}