{"id":"W2148038959","doi":"10.1002/jcp.21505","title":"Lipopolysaccharide plus hypoxia and reoxygenation synergistically reduce electrical coupling between microvascular endothelial cells by dephosphorylating Connexin40","year":2008,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"","keywords":"Phosphorylation; Lipopolysaccharide; Protein kinase C; Tyrosine phosphorylation; Protein kinase A; Hypoxia (environmental); Cell biology; Kinase; Tyrosine; Chemistry; Endocrinology; Biology; Internal medicine; Molecular biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161921,0.000487531,0.0002950662,0.0001485492,0.00008581387,0.0002049168,0.0001762695,0.0002020722,0.001142312],"category_scores_gemma":[0.0001270308,0.0001406042,0.0003668918,0.00007870958,0.0002130289,0.0002318687,0.0002964282,0.0005737429,0.0001455207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001400653,"about_ca_system_score_gemma":0.0001404557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002965548,"about_ca_topic_score_gemma":0.0004001153,"domain_scores_codex":[0.9997379,0.00005928822,0.00003204879,0.00004484846,0.00004521617,0.00008074417],"domain_scores_gemma":[0.9998493,0.00002662553,0.00004754759,0.00001900066,0.00001094508,0.00004646844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001916259,0.00003702924,0.00006401412,0.00003011969,0.000004732787,0.00002509627,0.000008194181,0.00004506667,0.9990368,0.00002847748,0.00001284666,0.0005159786],"study_design_scores_gemma":[0.00001952792,0.0009419647,0.002567673,0.000004154334,0.00001867146,0.00007522754,0.00001664744,0.0005468055,0.9953294,0.00002391169,0.0004527502,0.000003361053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966863,0.0007677274,0.001809588,0.00009294496,0.00002801169,0.0000211742,0.0001110174,0.00003437377,0.0004488506],"genre_scores_gemma":[0.9959109,0.0004988362,0.002278193,0.00005987697,0.00002252219,0.00005123948,0.0001510058,0.00001100137,0.001016452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142312,"threshold_uncertainty_score":0.003821433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01036454029366066,"score_gpt":0.2206178668217406,"score_spread":0.21025332652808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}