{"id":"W2148055079","doi":"10.1016/j.devcel.2009.08.006","title":"A Yeast Killer Toxin Screen Provides Insights into A/B Toxin Entry, Trafficking, and Killing Mechanisms","year":2009,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Biology; Toxin; Yeast; Clostridium difficile toxin A; Cell biology; Microbiology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105883,0.0002048473,0.0001366246,0.00007114105,0.0001509525,0.00006283582,0.0001905452,0.0001427001,0.00003831556],"category_scores_gemma":[0.00001401622,0.0001862344,0.00004553835,0.0001009051,0.00005217223,0.000006611915,0.0001640452,0.000113707,0.00003948788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003005126,"about_ca_system_score_gemma":0.0001090598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001619675,"about_ca_topic_score_gemma":0.00003821638,"domain_scores_codex":[0.9987631,0.00003793744,0.0001989152,0.0004404853,0.0002321386,0.0003273585],"domain_scores_gemma":[0.9995908,0.000005470198,0.00004054484,0.0001371675,0.00004737643,0.000178626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006696045,0.00009630598,0.0001344014,0.0000201437,0.0000166404,0.0000111517,0.0003996681,0.00001067093,0.9821237,0.0001027104,0.0007373376,0.01628029],"study_design_scores_gemma":[0.0005861105,0.0003324454,0.001521459,0.00002531418,0.000005399623,0.00001711726,0.0003343237,0.0001479288,0.97264,0.0003917098,0.02369449,0.0003037305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901596,0.001277791,0.001251565,0.0001018279,0.00008438393,0.0002615407,0.000004007342,0.00001997573,0.006839289],"genre_scores_gemma":[0.9847233,0.0003846801,0.01186339,0.0003976625,0.00008643051,0.00001182944,0.0001092974,0.00002070943,0.002402716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02295716,"threshold_uncertainty_score":0.7594419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00959932537419147,"score_gpt":0.2308307356860828,"score_spread":0.2212314103118913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}