{"id":"W2148122717","doi":"10.1016/s0305-7372(03)00020-3","title":"Marimastat may not improve survival over placebo following induction therapy for small-cell lung cancer Abstracted from: Shepherd F, Giaccone G, Seymour L et al. Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J Clin Oncol 2002; 20(22): 4434–39.","year":2003,"lang":"en","type":"letter","venue":"Cancer Treatment Reviews","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Lung cancer; Matrix metalloproteinase; Placebo; Oncology; Internal medicine; Randomized controlled trial; Cancer; Surgery; Gastroenterology; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008070183,0.0008261841,0.005320631,0.0003418455,0.0001714256,0.00005254774,0.0002096626,0.0003623173,0.0002850778],"category_scores_gemma":[0.0006221464,0.0004458601,0.001030287,0.0006711331,0.0003272482,0.0001228668,0.0000438173,0.0005157063,9.107354e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002888017,"about_ca_system_score_gemma":0.004331103,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.126727,"about_ca_topic_score_gemma":0.1904583,"domain_scores_codex":[0.9898808,0.004089543,0.00348009,0.001064816,0.0009844651,0.0005003008],"domain_scores_gemma":[0.9912945,0.003392969,0.00345518,0.0005099883,0.001188268,0.0001590781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9709168,0.00200861,0.005011287,0.0005509749,0.004817654,0.000004119258,0.0004790328,0.0001353966,0.0004433235,0.000001097761,0.008943964,0.006687724],"study_design_scores_gemma":[0.9572146,0.002619999,0.001130369,0.002058451,0.00405407,2.150568e-7,0.00002514349,0.0001101495,0.001720827,0.00000286049,0.03069682,0.0003664734],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8678745,0.00966047,0.00007963566,0.03451303,0.001093911,0.08210862,0.004591934,0.00001053954,0.00006734164],"genre_scores_gemma":[0.3067991,0.3699497,0.002176166,0.04715566,0.008472282,0.2417082,0.004026911,0.001126005,0.01858601],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5610754,"threshold_uncertainty_score":0.9997993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0863161860194505,"score_gpt":0.3984681189588007,"score_spread":0.3121519329393502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}