{"id":"W2148122717","doi":"10.1016/s0305-7372(03)00020-3","title":"Marimastat may not improve survival over placebo following induction therapy for small-cell lung cancer Abstracted from: Shepherd F, Giaccone G, Seymour L et al. Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J Clin Oncol 2002; 20(22): 4434–39.","year":2003,"lang":"en","type":"letter","venue":"Cancer Treatment Reviews","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Lung cancer; Matrix metalloproteinase; Placebo; Oncology; Internal medicine; Randomized controlled trial; Cancer; Surgery; Gastroenterology; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002592805,0.0005860687,0.001860962,0.0003907161,0.0008843254,0.001168119,0.0008348345,0.01347918,0.006021718],"category_scores_gemma":[0.01172605,0.0003469847,0.001137286,0.0005729999,0.0007558665,0.0008695754,0.0002923164,0.008897059,0.005678339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002543505,"about_ca_system_score_gemma":0.00127765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00236312,"about_ca_topic_score_gemma":0.005218014,"domain_scores_codex":[0.9985635,0.0005833905,0.0002342484,0.000153662,0.000329346,0.0001358762],"domain_scores_gemma":[0.9963543,0.002507494,0.0003710554,0.00007601435,0.0004403707,0.0002506402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.006624105,0.0001628225,0.001569127,0.0006105307,0.0001516961,0.004082927,0.00006729555,0.0001296765,0.001705835,0.001348481,0.891654,0.09189348],"study_design_scores_gemma":[0.0118677,0.002352581,0.01175252,0.001116672,0.0005908252,0.005018388,0.0001837683,0.001191944,0.002883998,0.006400892,0.9565526,0.00008820194],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.006396377,0.02289644,0.0002805581,0.9173028,0.04104378,0.0001269266,0.000835567,0.000130898,0.01098663],"genre_scores_gemma":[0.04412458,0.01718385,0.0005377347,0.8314635,0.0815982,0.0002536298,0.0003529688,0.000064065,0.02442152],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01347918,"threshold_uncertainty_score":0.02014464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0863161860194505,"score_gpt":0.3984681189588007,"score_spread":0.3121519329393502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}