{"id":"W2148135357","doi":"10.1158/1535-7163.mct-06-0134","title":"Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent","year":2006,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Ontario Genomics","funders":"National Institutes of Health","keywords":"Apoptosis; Pharmacology; Traditional medicine; Medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001484673,0.0003438675,0.000307136,0.00007822917,0.0001058371,0.00006913587,0.0003192647,0.00021514,0.00006049383],"category_scores_gemma":[0.00000544406,0.0003524542,0.0002316194,0.0001866176,0.0001275678,0.00001610394,0.0001130564,0.000136745,0.000003777086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005756401,"about_ca_system_score_gemma":0.0001735473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008955222,"about_ca_topic_score_gemma":0.0001172977,"domain_scores_codex":[0.9980074,0.00008237141,0.0004335234,0.0005881534,0.0003956917,0.000492911],"domain_scores_gemma":[0.9987419,0.000006647166,0.0002375458,0.0006877686,0.0002106914,0.0001154012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002340782,0.0002050773,0.0002792033,0.00002864599,0.0002475507,0.000008131316,0.00005784119,0.002257449,0.987549,0.001204738,0.00003778894,0.007890477],"study_design_scores_gemma":[0.0008122068,0.0004999411,0.0002467461,0.00003324807,0.0002124077,0.00001216894,0.00002749664,0.001064411,0.9563354,0.00111005,0.03923491,0.0004110406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763089,0.002560477,0.01978694,0.0002523091,0.0005003797,0.0003302592,0.00007285648,0.00003263288,0.0001552514],"genre_scores_gemma":[0.9944674,0.001216644,0.001337496,0.001855946,0.000427805,0.00006341661,0.0001490059,0.0001063808,0.0003758683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03919712,"threshold_uncertainty_score":0.9998928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01998035286368288,"score_gpt":0.2784638712500205,"score_spread":0.2584835183863376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}