{"id":"W2148144810","doi":"10.1261/rna.971208","title":"Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking","year":2008,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"EIF4G; EIF4E; eIF4A; Initiation factor; Eukaryotic initiation factor; Biology; Messenger RNA; Eukaryotic translation; EIF4A1; Cell biology; RNA Helicase A; Guanosine; eIF2; Translation (biology); Biochemistry; RNA; Helicase; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007620631,0.0001299155,0.0001024255,0.00003216973,0.000192407,0.00003555621,0.0001406441,0.0001137631,0.0001465749],"category_scores_gemma":[0.00005630875,0.0001273387,0.0000734708,0.00004541743,0.00003405903,0.00001146759,0.00005140415,0.00009255698,0.00006594595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002297964,"about_ca_system_score_gemma":0.00005159307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002674838,"about_ca_topic_score_gemma":0.0000134457,"domain_scores_codex":[0.9991565,0.00005429079,0.0001908171,0.0002611791,0.0001435121,0.0001936652],"domain_scores_gemma":[0.9995259,0.00001092877,0.00009705558,0.0002348134,0.00006576619,0.00006555031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002630744,0.0000440717,0.002476583,0.000009749382,0.00002622162,0.000006013788,0.00008697205,0.00001750121,0.9946271,0.00002435204,0.000551483,0.002103669],"study_design_scores_gemma":[0.0002147186,0.00008236964,0.0026882,0.0000176899,0.000007205917,0.00004592925,0.00001545083,0.00002455666,0.9904125,0.0001079454,0.006216596,0.0001668708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892833,0.0004633289,0.007265868,0.00007416019,0.000321589,0.0001914224,0.00003037581,0.00002802727,0.002341913],"genre_scores_gemma":[0.9958943,0.000178506,0.0004826748,0.0001757197,0.0002227151,0.00003453033,0.0001264207,0.00002379056,0.002861353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006783193,"threshold_uncertainty_score":0.519272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02355922010066103,"score_gpt":0.2743873226279556,"score_spread":0.2508281025272945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}