{"id":"W2148216326","doi":"10.1081/ncn-200027537","title":"Mitochondrial Function Dependent Proliferation Assay for the Diagnosis of Mitochondrial Disorders in Human Fibroblasts","year":2004,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Function (biology); Cell biology; Mitochondrion; Fibroblast; Mitochondrial disease; Chemistry; Biology; Mitochondrial DNA; In vitro; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001281777,0.00127489,0.0007147528,0.002211316,0.0006833685,0.0004756244,0.0008168338,0.0007893641,0.002864474],"category_scores_gemma":[0.0009675684,0.0003647849,0.0005455664,0.0008829807,0.0004597685,0.0005019294,0.0006584332,0.001671133,0.001293561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463615,"about_ca_system_score_gemma":0.0003949723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004393899,"about_ca_topic_score_gemma":0.001753662,"domain_scores_codex":[0.9987545,0.0003977594,0.0001536902,0.0001265458,0.0005021853,0.00006532735],"domain_scores_gemma":[0.998539,0.0006964303,0.0001589667,0.0001470431,0.000321943,0.0001366907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001211745,0.0001075926,0.0007275713,0.0001914783,0.00001992627,0.0001167728,0.00009508441,0.00007744971,0.9881533,0.0004097248,0.0002273137,0.009752647],"study_design_scores_gemma":[0.00002863703,0.000823152,0.004504792,0.00004995467,0.00008255548,0.0006749472,0.00006642902,0.001700634,0.9849507,0.0002874698,0.006802854,0.00002782712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4043045,0.0289619,0.5289752,0.0007524526,0.001354902,0.001805633,0.005033264,0.002934704,0.02587735],"genre_scores_gemma":[0.4786669,0.02040791,0.4532558,0.0004173722,0.0004280567,0.003138548,0.008669563,0.0002536691,0.03476219],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002864474,"threshold_uncertainty_score":0.009582639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103367908536964,"score_gpt":0.2493050373612342,"score_spread":0.2382713582758645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}