{"id":"W2148216326","doi":"10.1081/ncn-200027537","title":"Mitochondrial Function Dependent Proliferation Assay for the Diagnosis of Mitochondrial Disorders in Human Fibroblasts","year":2004,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Function (biology); Cell biology; Mitochondrion; Fibroblast; Mitochondrial disease; Chemistry; Biology; Mitochondrial DNA; In vitro; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003418466,0.0003977463,0.0004040079,0.0001768409,0.0003655577,0.00007997132,0.0004513696,0.0004307631,0.0001474235],"category_scores_gemma":[0.0004920646,0.0003428906,0.0003557659,0.0002523171,0.0002819735,0.0000406035,0.0001458327,0.0002607074,0.00002259826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007709443,"about_ca_system_score_gemma":0.0001094934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001738399,"about_ca_topic_score_gemma":0.002859734,"domain_scores_codex":[0.9973989,0.0001956878,0.0007866536,0.0007675199,0.0003296683,0.0005215366],"domain_scores_gemma":[0.9985583,0.0001479801,0.0003180149,0.0006926566,0.0001655305,0.000117548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002199815,0.0005146348,0.01066499,0.00007818619,0.0001619205,0.000001850447,0.0003739223,0.00794975,0.9659755,0.004109558,0.004055518,0.003914375],"study_design_scores_gemma":[0.02970016,0.01101913,0.04411605,0.0003972796,0.0007039894,0.00007217811,0.001571195,0.0008504157,0.7631074,0.02000909,0.1259575,0.002495622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9375674,0.0003235492,0.05337409,0.001195694,0.003896342,0.002793605,0.00009283502,0.00008037985,0.000676115],"genre_scores_gemma":[0.9926788,0.0001532914,0.004267382,0.0003839904,0.001500205,0.0005567114,0.0001636204,0.00009873181,0.0001972166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.202868,"threshold_uncertainty_score":0.9999023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103367908536964,"score_gpt":0.2493050373612342,"score_spread":0.2382713582758645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}