{"id":"W2148378265","doi":"10.1098/rstb.2002.1081","title":"Structure and function of antifreeze proteins","year":2002,"lang":"en","type":"review","venue":"Philosophical Transactions of the Royal Society B Biological Sciences","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Antifreeze protein; van der Waals force; Binding site; Chemistry; Hydrogen bond; Biophysics; Mutagenesis; Protein structure; Crystallography; Biology; Biochemistry; Molecule; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001960669,0.0002812254,0.0007498233,0.00001262067,0.0003920693,0.00001323017,0.0007017407,0.000471351,0.001330128],"category_scores_gemma":[0.00005891103,0.0001235379,0.0008487952,0.0007535587,0.004249304,0.00005392825,0.000154256,0.0004881398,0.000008063831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000356377,"about_ca_system_score_gemma":0.00001581779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004499525,"about_ca_topic_score_gemma":0.000001380512,"domain_scores_codex":[0.9981667,0.0001705913,0.0005013612,0.0005287958,0.000376838,0.0002557551],"domain_scores_gemma":[0.9991072,0.0002588569,0.0003105009,0.0002116207,0.00001390699,0.00009787022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00001898581,0.000853819,0.0003090501,0.001678187,0.0002277618,3.302464e-7,0.00005962227,0.0004991204,0.004110813,0.001700593,0.000172738,0.990369],"study_design_scores_gemma":[0.0014686,0.007701808,0.01383588,0.007725605,0.004246545,0.0000515408,0.0001421529,0.007490152,0.003498366,0.5741094,0.3750136,0.004716307],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01503391,0.9774157,0.001617093,0.001499564,0.0002923418,0.00182928,0.0006553165,0.00008582375,0.001570904],"genre_scores_gemma":[0.3892612,0.6092955,0.001195033,0.0000686743,0.00006964597,0.00003217582,0.000006784312,0.000006821678,0.00006415571],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9856527,"threshold_uncertainty_score":0.9995828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0739707774705568,"score_gpt":0.2691563302718315,"score_spread":0.1951855528012747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}