{"id":"W2148480736","doi":"10.1038/embor.2009.98","title":"Overgrowth of a mouse model of Simpson– Golabi–Behmel syndrome is partly mediated by Indian Hedgehog","year":2009,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Hedgehog; Indian hedgehog; Hedgehog signaling pathway; Endocrinology; Biology; Internal medicine; Null allele; Mutant; Cell biology; Genetics; Signal transduction; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002605258,0.001284682,0.0005074651,0.00183433,0.0003533385,0.0005987558,0.0004874694,0.0010554,0.002700811],"category_scores_gemma":[0.0002206316,0.0006696484,0.0006950321,0.0004090998,0.0007840662,0.0003783835,0.0006980081,0.001811964,0.0008220197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004583359,"about_ca_system_score_gemma":0.0005019177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001341016,"about_ca_topic_score_gemma":0.002193065,"domain_scores_codex":[0.9994099,0.00009866185,0.0000562911,0.0001105223,0.0002096089,0.0001150743],"domain_scores_gemma":[0.9991805,0.00009929299,0.0002566412,0.00009895457,0.00003435865,0.0003302558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002740554,0.0000542376,0.0001890744,0.00002933054,0.0000113055,0.0003648679,0.00002205158,0.00006359635,0.9981629,0.0001956952,0.00006661905,0.0005662751],"study_design_scores_gemma":[0.0001634158,0.0005909071,0.007020711,0.0000271956,0.00009480155,0.002779707,0.0001565433,0.001638623,0.9833907,0.0003612405,0.003748947,0.00002707976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936748,0.001344503,0.001728352,0.0003136369,0.00008718357,0.00002860026,0.0009321077,0.0002503647,0.001640357],"genre_scores_gemma":[0.9878498,0.001109509,0.002286452,0.0001180342,0.00002634963,0.00005989234,0.0007481115,0.0001357608,0.007666096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002700811,"threshold_uncertainty_score":0.00903511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007241860442712335,"score_gpt":0.223233290584847,"score_spread":0.2159914301421347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}