{"id":"W2148547695","doi":"10.1038/sj.onc.1203731","title":"G2A is an oncogenic G protein-coupled receptor","year":2000,"lang":"en","type":"article","venue":"Oncogene","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; Medical Research Council Canada","keywords":"RHOA; Biology; Cell biology; Signal transduction; Transfection; GTPase; G protein; Gq alpha subunit; RAC1; 3T3 cells; Cell growth; Oncogene; Molecular biology; Cell; Cell culture; Cell cycle; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009013295,0.000550852,0.0002380503,0.000490966,0.0004632578,0.0004714329,0.0003029127,0.0004340151,0.002418861],"category_scores_gemma":[0.00008954919,0.0001474761,0.0003035033,0.0005103161,0.0004305787,0.0002066787,0.0002949763,0.0006466798,0.001952253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008880072,"about_ca_system_score_gemma":0.0005003524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002052814,"about_ca_topic_score_gemma":0.002201875,"domain_scores_codex":[0.9999081,0.00001631668,0.000003576361,0.00001870913,0.00002185167,0.00003149658],"domain_scores_gemma":[0.9999748,0.00000235598,0.000005613414,0.000003372881,0.000002912556,0.0000109913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007855256,0.0001845165,0.001455828,0.000210284,0.00006348287,0.001855109,0.00004294442,0.0007086035,0.9628075,0.008821351,0.007494123,0.01557069],"study_design_scores_gemma":[0.0001948831,0.0008031805,0.01366781,0.00004136677,0.0001559581,0.005751212,0.0001941275,0.002542464,0.7576546,0.002051577,0.216908,0.00003471625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9219787,0.01878033,0.007259286,0.005379543,0.000898372,0.000228204,0.006090696,0.001104067,0.03828073],"genre_scores_gemma":[0.968325,0.007977439,0.003063613,0.0004231845,0.00008441981,0.0001081246,0.004104253,0.0000382056,0.01587593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002418861,"threshold_uncertainty_score":0.008091927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364388179431897,"score_gpt":0.2664014186574728,"score_spread":0.2527575368631538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}