{"id":"W2148557114","doi":"10.1371/journal.ppat.1003403","title":"The Escherichia coli Phosphotyrosine Proteome Relates to Core Pathways and Virulence","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Wilfrid Laurier University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Council of Scientific and Industrial Research, India; National Institute of Allergy and Infectious Diseases; Johns Hopkins University","keywords":"Tyrosine phosphorylation; Phosphorylation; Tyrosine; Biology; SH2 domain; Proteome; Biochemistry; Protein phosphorylation; Protein tyrosine phosphatase; Receptor tyrosine kinase; Tyrosine kinase; Signal transduction; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919454,0.0001899121,0.000150547,0.00001895113,0.0003926318,0.0000873192,0.000261177,0.00009860447,0.00001911236],"category_scores_gemma":[0.0006618543,0.0001319198,0.00004687571,0.0001645666,0.0001921591,0.000006039245,0.0004537432,0.0001514937,0.00008909141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001577879,"about_ca_system_score_gemma":0.00005905607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003090742,"about_ca_topic_score_gemma":0.00003024079,"domain_scores_codex":[0.9987108,0.00005752248,0.0001793562,0.0003927049,0.0002139297,0.0004457309],"domain_scores_gemma":[0.9990621,0.00005291951,0.00005375808,0.0004253035,0.0002139357,0.0001919516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003400712,0.00004573794,0.004231472,0.00001718437,0.00005559935,0.000003202005,0.0001314312,0.000002282153,0.9926562,0.0001100477,0.001811286,0.0009015537],"study_design_scores_gemma":[0.0006021053,0.001264549,0.09448807,0.00006798867,0.00004023581,0.000007886359,0.0005360829,0.0006917606,0.8718898,0.000665926,0.02911415,0.0006313933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951068,0.002186704,0.00004870767,0.000815963,0.0000496695,0.001056798,0.00003353718,0.00002750878,0.0006743628],"genre_scores_gemma":[0.9936321,0.001389652,0.002350661,0.0004847132,0.0001157976,0.0008968338,0.00001150362,0.00003440757,0.001084313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1207663,"threshold_uncertainty_score":0.5379534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02042973251304852,"score_gpt":0.2397557087848586,"score_spread":0.2193259762718101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}