{"id":"W2148557114","doi":"10.1371/journal.ppat.1003403","title":"The Escherichia coli Phosphotyrosine Proteome Relates to Core Pathways and Virulence","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Wilfrid Laurier University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Council of Scientific and Industrial Research, India; National Institute of Allergy and Infectious Diseases; Johns Hopkins University","keywords":"Tyrosine phosphorylation; Phosphorylation; Tyrosine; Biology; SH2 domain; Proteome; Biochemistry; Protein phosphorylation; Protein tyrosine phosphatase; Receptor tyrosine kinase; Tyrosine kinase; Signal transduction; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007159187,0.0003332765,0.0001541982,0.0002453517,0.0001612145,0.0002993052,0.0001075807,0.0002981849,0.0004932842],"category_scores_gemma":[0.0001069144,0.0001211216,0.0001814963,0.0002748142,0.0001587031,0.0002100048,0.000191732,0.0002320375,0.000244264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679214,"about_ca_system_score_gemma":0.0001752827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006064435,"about_ca_topic_score_gemma":0.000549711,"domain_scores_codex":[0.9999255,0.00000886596,0.000005090369,0.00002200788,0.0000175506,0.00002102351],"domain_scores_gemma":[0.9999321,0.00000872912,0.00002597075,0.000006407902,0.00001107583,0.00001567878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007415453,0.00000632246,0.0009899357,0.00002291461,0.000002774643,0.00003295348,0.000009254297,0.00004973778,0.998026,0.00002886335,0.00001034606,0.0007468423],"study_design_scores_gemma":[0.000006984509,0.0001976375,0.1788299,0.00001209087,0.00002867155,0.001071219,0.00010412,0.002038561,0.8157349,0.0002767142,0.001687974,0.00001116398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962131,0.000982722,0.001847366,0.00005031344,0.000004560435,0.000009162653,0.0003781468,0.00002277706,0.000491929],"genre_scores_gemma":[0.996578,0.000578377,0.001642367,0.0000322352,0.000004009316,0.00000887942,0.0005729808,0.000008590378,0.000574536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006064435,"threshold_uncertainty_score":0.001650214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02042973251304852,"score_gpt":0.2397557087848586,"score_spread":0.2193259762718101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}