{"id":"W2148578075","doi":"10.1016/j.cell.2015.03.029","title":"The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":258,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Fondation Brain Canada","keywords":"Depolarization; Intracellular; Edema; Biology; Cytotoxic T cell; Biophysics; Programmed cell death; Premovement neuronal activity; Swelling; Membrane potential; Cell biology; Neuroscience; Pharmacology; Apoptosis; Biochemistry; Pathology; Internal medicine; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003025035,0.0004888083,0.0003990516,0.000483776,0.0004278025,0.0009212116,0.000688278,0.0006604698,0.000587943],"category_scores_gemma":[0.0002760255,0.0001460306,0.0002686757,0.0002570018,0.0009645224,0.001767101,0.0004654042,0.0007947441,0.0002187583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007074387,"about_ca_system_score_gemma":0.0003695921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003773853,"about_ca_topic_score_gemma":0.0003644498,"domain_scores_codex":[0.9998196,0.00003137233,0.00001480331,0.00001995756,0.00005555484,0.00005879642],"domain_scores_gemma":[0.9998527,0.00003275295,0.00004497869,0.00001812986,0.00002764336,0.00002385617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007512302,0.0001175208,0.001681621,0.0004965025,0.00003373606,0.002374011,0.000344663,0.001461983,0.9527614,0.02227183,0.000713561,0.01699193],"study_design_scores_gemma":[0.0000621864,0.0006996759,0.02548217,0.0001010716,0.0000946381,0.004626086,0.0009875337,0.005882146,0.9246399,0.02804615,0.009320962,0.00005734794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8855196,0.05401708,0.04297646,0.004515378,0.0004582264,0.0001490725,0.0004814564,0.0004580658,0.0114246],"genre_scores_gemma":[0.9863782,0.01013889,0.001544998,0.0002080598,0.0001038672,0.00004083114,0.00009029579,0.00001017739,0.001484738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009212116,"threshold_uncertainty_score":0.005132794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03789616344682192,"score_gpt":0.2484408188903759,"score_spread":0.210544655443554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}