{"id":"W2148578075","doi":"10.1016/j.cell.2015.03.029","title":"The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":258,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Fondation Brain Canada","keywords":"Depolarization; Intracellular; Edema; Biology; Cytotoxic T cell; Biophysics; Programmed cell death; Premovement neuronal activity; Swelling; Membrane potential; Cell biology; Neuroscience; Pharmacology; Apoptosis; Biochemistry; Pathology; Internal medicine; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948246,0.00006293267,0.00005031095,0.00001435882,0.000073395,0.00001235918,0.00008629168,0.00006553454,0.000008161614],"category_scores_gemma":[0.00002209769,0.00004842368,0.00004709738,0.00004208195,0.00003079264,0.000001748741,0.00003439892,0.00003899556,0.00001476937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006346149,"about_ca_system_score_gemma":0.00003924288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002218639,"about_ca_topic_score_gemma":0.000001301171,"domain_scores_codex":[0.9995055,0.00003569955,0.0001182018,0.0001221071,0.0001113802,0.0001071597],"domain_scores_gemma":[0.9996541,0.000009419883,0.0000624345,0.0001524943,0.00007027064,0.0000512694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000316451,0.00001488517,0.000009959762,0.000005495041,0.000004790108,3.384862e-7,0.00002659776,0.001437061,0.9969652,0.0004971891,0.000763091,0.0002436943],"study_design_scores_gemma":[0.0002590381,0.0001256969,0.00002233734,0.000002299466,0.00000520184,0.000001312965,0.0002135694,0.00303241,0.9783891,0.001470377,0.01641757,0.00006102887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7493752,0.0004297723,0.2437535,0.0001551285,0.001147187,0.0001348284,0.000002101175,0.00001269477,0.004989578],"genre_scores_gemma":[0.9969102,0.00002571419,0.0003035164,0.00007693734,0.0001636056,0.000003551986,0.0000247258,0.00001058335,0.002481142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.247535,"threshold_uncertainty_score":0.197466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03789616344682192,"score_gpt":0.2484408188903759,"score_spread":0.210544655443554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}