{"id":"W2148598128","doi":"10.1242/dev.00410","title":"Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice","year":2003,"lang":"en","type":"article","venue":"Development","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Biology; RAD51; DNA repair; Spermatogenesis; Homologous recombination; DNA damage; Homologous chromosome; Genetics; Mutant; Meiosis; Molecular biology; Cell biology; Gene; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003429194,0.0001948996,0.0002061256,0.00008723829,0.00009862944,0.00002622996,0.0001079881,0.0001247989,0.00002531551],"category_scores_gemma":[0.00007067982,0.0001969996,0.00006568205,0.0001316201,0.00007013403,0.000006352963,0.000135922,0.00005407279,0.000006453835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000759098,"about_ca_system_score_gemma":0.0002094297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001006482,"about_ca_topic_score_gemma":0.00008998681,"domain_scores_codex":[0.9986435,0.00005097407,0.0003967026,0.0003976819,0.0001757717,0.0003353539],"domain_scores_gemma":[0.9994769,0.000008535004,0.0001035349,0.0002766547,0.00004836151,0.00008608056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000610498,0.0001275873,0.01616175,0.0001362585,0.0000538278,0.00001862677,0.0006761077,0.00003595826,0.9822602,0.00008536159,0.00005933479,0.0003239912],"study_design_scores_gemma":[0.0007881913,0.00005563399,0.11902,0.00004431752,0.000009361825,0.00004242255,0.0001933396,0.00005348826,0.8767571,0.00001314322,0.002790171,0.0002328723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998809,0.000390632,0.0001040392,0.00001143649,0.00008671226,0.0002122631,0.000004684447,0.00002435381,0.0003568586],"genre_scores_gemma":[0.9901611,0.00003887924,0.009282433,0.00007481752,0.00001066145,0.00001659263,0.0000161823,0.00002602113,0.0003732644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1055031,"threshold_uncertainty_score":0.8033412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377924775420465,"score_gpt":0.243375592772066,"score_spread":0.2295963450178614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}