{"id":"W2148626203","doi":"10.1083/jcb.201103168","title":"Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype","year":2011,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Cancer Research UK; Wellcome Trust; Howard Hughes Medical Institute","keywords":"Biology; RNA interference; Phenotype; Genetics; Computational biology; Evolutionary biology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006717439,0.0001146339,0.0002492473,0.00004406089,0.0001064108,0.00001086033,0.0004187185,0.00009013663,0.00008186032],"category_scores_gemma":[0.00006437083,0.00007009587,0.00009966389,0.00006092394,0.00023409,0.00000619564,0.0001026212,0.000225797,0.00001086912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006665912,"about_ca_system_score_gemma":0.00006239777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009413391,"about_ca_topic_score_gemma":0.00002985325,"domain_scores_codex":[0.9990188,0.0002664218,0.0002829973,0.0001039101,0.00008525324,0.0002425597],"domain_scores_gemma":[0.9991451,0.00006896542,0.0003093549,0.0001869098,0.0001984246,0.00009123117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006706314,0.00003819766,0.0007331267,0.000004458976,0.0001463843,0.000003352328,0.0002678557,0.000003389167,0.9956056,0.00001773811,0.002266061,0.0002432387],"study_design_scores_gemma":[0.0005451742,0.0008649732,0.001051651,0.000007276763,0.00003691403,0.00004844536,0.0006672689,0.00002702939,0.9923979,0.0001769669,0.004084209,0.00009220526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929315,0.003053363,0.001737208,0.00006589793,0.0001052128,0.00007855298,0.000008139006,0.00000258907,0.002017503],"genre_scores_gemma":[0.9976166,0.0004418799,0.0005274558,0.0001633351,0.000101592,0.000001238967,0.00001189282,0.000008522813,0.001127412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004685137,"threshold_uncertainty_score":0.2858427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07965947280707016,"score_gpt":0.3144245603824674,"score_spread":0.2347650875753973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}