{"id":"W2148632293","doi":"10.1093/clinchem/48.8.1147","title":"Cancer Biomarkers: Easier Said Than Done","year":2002,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Biomarker; Biomarker discovery; Cancer biomarkers; Standardization; Cancer; Terminology; Medicine; Bioinformatics; Computer science; Biology; Internal medicine; Proteomics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.024417,0.001909177,0.003137544,0.003171147,0.002097598,0.01035283,0.001935532,0.007577589,0.01493799],"category_scores_gemma":[0.03194336,0.0007576015,0.001333832,0.002096596,0.01034218,0.01911465,0.004038455,0.01224129,0.009269226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002585718,"about_ca_system_score_gemma":0.004274314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001382961,"about_ca_topic_score_gemma":0.001196795,"domain_scores_codex":[0.9880363,0.005760235,0.001123495,0.001083927,0.003588463,0.000407479],"domain_scores_gemma":[0.9768279,0.01146602,0.00138727,0.002568453,0.006339056,0.001411449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003576091,0.0001621372,0.003073144,0.007004051,0.0004840147,0.0009289617,0.001291016,0.0006806694,0.004430457,0.2163234,0.2563963,0.5088682],"study_design_scores_gemma":[0.00004867105,0.0001462644,0.0007171364,0.002683524,0.00009338761,0.001560374,0.0009049746,0.0002570898,0.001366839,0.1530801,0.8390555,0.00008624446],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001848186,0.4156462,0.0482536,0.4738063,0.03986004,0.0001649292,0.0004102444,0.0006032923,0.01940713],"genre_scores_gemma":[0.06722307,0.4576136,0.1195389,0.2616372,0.05076329,0.0005791353,0.0008623111,0.0006219292,0.04116054],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.024417,"threshold_uncertainty_score":0.129131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09455864515885498,"score_gpt":0.3784568846899853,"score_spread":0.2838982395311304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}